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Biomedical subjects

A M Freedman

Publications and source records attributed to A M Freedman.

At least 73 records · Page 4Linked to original sources
PubMed1980

Psychopharmacology and psychotherapy in the treatment of anxiety.

The symptom of anxiety, perhaps the most common in all clinical medicine, presents in a variety of forms--psychologic, somatic, behavioral--and often masquerades or is misdiagnosed. Anxiety is a manifestation encountered in a heterogeneous group of syndromes or disorders embracing all of psychiatry. It is necessary to develop the best treatment or combination of treatments appropriate for each case or group of cases. In the treatment of anxiety controlled comparative studies indicate that patients receiving psychotherapy do better than controlled groups. According to present knowledge no one method of psychotherapy is superior to others. The effectiveness of pharmacotherapy alone in the treatment of anxiety is unequivocally established. However, combined therapy of pharmacologic agents and psychotherapy would appear to be superior to either therapy alone. Critical research using existing modalities and combinations of modalities is of vital importance in the treatment of anxiety. Rapid developments in the past twenty-five years in the discovery and differential use of pharmacotherapeutic agents have stimulated renewed interest in the anxiety states and related disorders, as has the emerging body of knowledge regarding possible specific receptor sites in the brain related to anxiety. These developments have heightened interest in research on anxiety with resulting innovations in treatment.

Anxiety↗
PubMed1977

Medical student education in psychiatry.

The authors interpret data obtained from 99 medical schools which submitted grant applications for support of either undergraduate psychiatric education programs or human behavior programs. They tentatively conclude that high-quality programs for teaching medical students psychiatry are characterized by a well-rounded faculty, a psychodynamic orientation, a greater commitment to medical student education than to resident training, varied teaching methods, enthusiastic student response, and systematic evaluation that produces change in subsequent years.

Attitude of Health Personnel↗
PubMed1977

Research training in psychiatry.

The authors examined data on 13 requests for federal support for psychiatric research investigation that were evaluated as part of the NIMH review of psychiatric education grants in fiscal year 1975. Thirteen factors were found to be associated with quality of psychiatric research training, and the interaction and importance of these factors are illustrated in summaries of 5 programs. The ideal program is described as one in which there is a clearly stated concept, content that is broad and relevant enough to interest trainees in psychiatry, a continuing evaluation process, and superior research that can be documented. Adequate depth and breadth in terms of faculty and facilities are also essential. The authors believe that all psychiatrists should be encouraged to integrate scientific observation into their professional work and to evaluate systematically the effectiveness of their clinical interventions.

Curriculum↗
PubMed1976

Chronic hashish use and mental disorder.

The authors compared 47 long-term users of hashish with a control group of 40 subjects matched for age, ethnic origin, education, etc., in order to determine whether they differed significantly on psychiatric, physical health, and demographic variables. There was a significantly higher incidence of personality disorders, unemployment, and prison sentences in the group of chronic users. However, in contrast to the findings of other researchers, the hashish users did not have organic psychoses, nor did they differ from control subjects in neurologic signs or EEG and echo encephalogram patterns.

Adult↗
PubMed1976

l-Alpha-acetylmethadol (LAAM): prognostic considerations.

The authors studied the responses of 28 adult male volunteers who were openly changed from methadone to l-alpha-acetylmethadol (LAAM) maintenance. They found that patients who had been receiving middle-range doses (50-70 mg) of methadone required a significantly lower mean increase in LAAM than patients who had been receiving either high or low methadone doses and that the patients who accepted LAAM differed significantly from those who did not in MMPI 2-point-code ratings and mean social adjustment scale scores. These findings may provide prognostic indicators for response to LAAM, a possible alternative to methadone.

Heroin Dependence↗
PubMed1976

Short-term effects of naltrexone in 155 heroin ex-addicts.

The narcotic antagonist naltrexone was administered for periods of up to 8 months to a total of 155 patients at a dose of 40-200 mg per day. The antagonistic effect of naltrexone was tested by injections of heroin. Eighty milligrams of natrexone was effective for 48hr. The antagonistic effect decreased at 72 hr after the administration of 120-200 mg of naltrexone. Laboratory tests indicated no signs of toxicity. Naltrexone may elicit an increase in blood pressure and opigastric pain. Neither of these side effects appear clinically important. No signs of dependence on naltrexone were detected. These results suggest that naltrexone may be useful for clinical treatment of opiate dependence.

Abdomen↗