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Biomedical subjects

A M Gadzhiev

Publications and source records attributed to A M Gadzhiev.

8 recordsLinked to original sources
PubMedDate not supplied

[Pro- and antioxidant effect of electromagnetic fields of extremely high frequency (460 MHz) on brain tissues in experiment].

The article concerns biological effects of non-ionized electromagnetic irradiation which is considered in modern world as a serious ecological factor. Influence of decimetric microwave irradiation (460 MHz) on free radical processes in the rat brain tissues--visual cortex and hypothalamus--were investigated. Oxidative effects of both lipid peroxidation and specific activity of glutathione reductase were determined. It is shown that whole body irradiation for up to 4 weeks results in considerable changes of the above indices dependent on the irradiation intensity and age of the animals. Decimetric microwaves have oxidant effects at high intensity irradiation (SAR--15 mW/kg), while these effects are antioxidant at low intensity (SAR--5 mW/kg). Physiological implications of different oxidative metabolic responses of the hypothalamus and the cortex to microwaves irradiation are discussed.

Animals↗
PubMedDate not supplied

[Influence of (460 MHz) electromagnetic fields on the induced lipid peroxidation in the structures of visual analyzer and hypothalamus in experimental animals].

Changes in the intensity of ascorbate- and NADPN2-dependent induced lipid peroxidation (LPO) were studied in exposure of the visual analyzer and hypothalamus of 3- and 12-month-old rats to radiation with microwaves of high and low intensity. The exposure to microwaves of high intensity stimulated basal LPO but suppressed activity of LPO-inducing systems. This suggests disturbances in the activity of different sources of active oxygen forms. Microwaves of low intensity activated systems of induced LPO. This is accompanied with synchronous activity of the antioxidant defense system maintaining a normal oxidation-reduction balance of the cell. The conclusion is that, depending on their intensity, microwaves can be either beneficial to health or be a factor of oxidative stress.

Animals↗
PubMedDate not supplied

[Small-angle diffuse x-ray scattering on fine muscle filaments].

Theoretical small-angle diffuse scattering curves from muscle thin filament models have been calculated. The curves reveal a maximum at 115' scattering angle. It has been shown that the maximum is due to the pitch of F-actin helix. Theoretical curves are in good agreement with the earlier obtained curves of small-angle diffuse scattering from F-actin dilute solutions.

Actins↗
PubMedDate not supplied

[Interpretation of the diffraction picture of a skeletal muscle during the active phase of contraction].

New data concerning changes in the diffraction patterns at muscle activation, obtained by X-ray studies with a high resolution rate helped to interpret the diffraction patterns of the skeletal muscle in the active phase of contraction. Changes in the intensity of the meridianal reflex 143 A at the time of isomeric contractions and during rapid mechanical muscle stimulus are discussed. Experimental data analysis and calculations of the diffraction pattern, corresponding to the states of rest and contraction, showed, that the observed changes can be explained by the model of contactless interaction of myosin bridges with fine fibers. The diffraction pattern at the active phase of contraction showed that the bridges are near the fine fiber, but are not attached to the specific centers of binding on the actin globules.

Animals↗
PubMedDate not supplied

[Use of linear proportional chambers for small-angle synchrotron radiation scattering in solutions of biopolymers].

The results of applying linear position sensitive proportional counters to diffuse small-angle synchrotron radiation scattering to biopolymer solutions are presented. Synchrotron radiation of the VEPP-3 storage ring (Institute of Nuclear Physics, Novosibirsk) was used. On the basis of small-angle scattering curve obtained from protein pepsinogen it has been shown that the exposure is about 100 times less than with conventional X-ray technique.

X-Ray Diffraction↗