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Biomedical subjects

A M Goncharenko

Publications and source records attributed to A M Goncharenko.

13 recordsLinked to original sources

Modifications of spontaneous oculomotor activity in microgravitational conditions.

Investigations on spontaneous oculomotor activity were carried out prior to and after (five cosmonauts) and during space flight (two cosmonauts) on the 3rd, 5th and 164th days of the space flight. Recording of oculomotor activity was carried out by electrooculography on automated data acquisition and processing system "Zora" based on personal computers. During the space flight and after it all the cosmonauts with the eyes closed or open and dark-goggled showed an essential increase of the movements' amplitude when removing the eyes into the extreme positions especially in a vertical direction, occurrence of correcting saccadic movements (or nystagmus), an increase in time of fixing reactions.

Eye Movements↗

[Radical correction of tetralogy of Fallot after palliative operations].

The experience in radical correction of tetralogy of Fallot in 120 patients after various palliative operations is generalized. Twenty-five patients (20.8%) died. From comparative evaluation of the different preceding operations, preference cannot be given to any of the anastomoses. From the standpoint of the subsequent radical correction, Potts' anastomosis is the most disadvantageous palliative intervention.

Adolescent↗

[Pattern of spontaneous oculomotor activity in weightlessness and the readaptation period].

The results of one part Spontaneous Oculomotor Activity Study of Soviet-Bulgarian experiment "Labyrinth" conducted with the participation of 5 cosmonauts prior to and after 10- and 241-day flight are presented. Two cosmonauts have also been studied in-flight. The experiment was conducted with the use of automated data controlling and processing system "Zora" developed by the Bulgarian specialists on a personal computer basis. The horizontal and vertical electrooculograms were recorded in the subjects with eyes closed, open and open but shaded by opaque glasses with the gaze directed forward and in extreme left, right, up and down directions of the gaze. It is found that in the first 3 day of space flight especially when locking visual input, there is an increase in spontaneous activity of "swimming" and saccadic nature or spontaneous nystagmus mainly in the vertical direction. There have been sharp decreases in the rate of eye movement and increase of an amplitude when placing the eyes in the extreme positions (especially in up-down directions) accompanied by correcting saccades or adaptive nystagmus. The post- and inflight changes in the severity and pattern of spontaneous oculomotor responses were similar.

Adaptation, Ocular↗

[Vestibular function and interanalyzer interaction following space flight].

This paper presents the results of pre- and post-flight vestibular examinations using single and combined vestibular, optokinetic, proprioceptive, postural tests and cerebellar coordination tests. After extended flights most crewmembers showed spontaneous, position and positional nystagmus that points to vestibular dysfunction. The methods developed by the authors helped differentiate mechanisms of post-flight vestibular dysfunctions: in Group 1 subjects spontaneous nystagmus parameters varied during all tests; in Group 2 subjects they varied only in response to active tilt tests; in Group 3 subjects they varied only in response to vestibular, optovestibular and proprioceptive stimulation; and in Group 4 subjects they varied only in response to proprioceptive optovestibular stimulation and cerebellar coordination tests. Individual patterns of the above changes are associated with different pathways of adaptation of the vestibular function that depend on the involvement of various structures and compartments of the central nervous system.

Eye Movements↗

[Changes in sleep with different types of reaction to emotional stress].

Polygraphic study of night sleep, carried out on 21 students the night after an examination and one night after vacations, revealed two types of reactions to an emotional stress. It has been shown that in the case of a rapid normalization of vegetative and electromyographic manifestations following the end of an emotional stress impact, the structure of night sleep remains unchanged. When manifestations of the emotional stress persist after the elimination of the stress situation, the amount of the rapid sleep in the following night increases. It is suggested that the differences noted are related to different types of anxiety stress.

Adult↗