[Functional rehabilitation of the paraplegic].
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Activities of Daily Living↗
Biomedical subjects
A M Hansen
Publications and source records attributed to A M Hansen.
Towards independence for paraplegics.
Good rehabilitation emphasizes the abilities rather than the disabilities of the paraplegic and promotes the greatest level of self-care and independence possible. However, even with a level of independence, there still exist societal barriers that prevent the disabled from assuming a greater involvement in the community. Educating the government and the public, about the need for more and better suitable housing, more vocational opportunities, fewer physical barriers such as high curbs, stairs and narrow doorways that prevent access to public and commercial buildings and trying to encourage positive attitudes toward the disabled will help bring the paraplegic out of isolation and allow him to develop a full, active life.
Activities of Daily Living↗
Attempt to separate the fluorescence spectra of adrenaline and noradrenaline using chemometrics.
An investigation was conducted on whether the fluorescence spectra of the very similar catecholamines adrenaline and noradrenaline could be separated using chemometric methods. The fluorescence landscapes (several excitation and emission spectra were measured) of two data sets with respectively 16 and 6 samples were measured, the smaller data set with higher resolution and i.e. precision. The samples were artificial urine (pH approximately equal to 3) spiked with the catecholamines in the concentration ranges 40--1200 nmol/L and 5.5--18 micromol/L, respectively. Unfold partial least squares regression (Unfold-PLSR) on the larger data set and parallel factor analysis (PARAFAC) of the six samples of the smaller set showed that there was no difference between the fluorescence landscapes of adrenaline and noradrenaline. It can be concluded that chemometric separation of adrenaline and noradrenaline is not obtainable using this type of fluorescence measurement. Raman scatter, which overlaps the catecholamine spectra, was shown not to have any influence on the models calculated.
Calibration↗
Determination of 1-hydroxypyrene in human urine by high-performance liquid chromatography.
A high-performance liquid chromatography (HPLC)/fluorescence method for quantitative analysis of 1-hydroxypyrene in urine was developed. The method validation analysis showed the method to be in analytical control. No significant systematical errors could be demonstrated. The entire run time of chromatography was 10 min using isocratic elution (acetonitrile-water, 70:30), and the retention time for 1-hydroxypyrene was 3.5 min. The short run time in combination with the low limit detection (1.37 nmol/L) makes the method potentially applicable for surveillance of pyrene exposure in work environments. The developed method is presently used for measurement of 1-hydroxypyrene in urine samples from workers exposed to a low airborne level of polycyclic aromatic hydrocarbons, generally less than 25 micrograms/m3. The urine samples of exposed workers (n = 122) showed a range of 1-hydroxypyrene from the limit of detection (LD) up to 39 nmol/L, whereas unexposed control individuals (n = 108) showed a range from LD to 3.3 nmol/L.
Chromatography, High Pressure Liquid↗
The diagnostic evaluation and therapy of secondary amenorrhea.
One of the greatest challenges to health-care providers for women is the diagnostic evaluation and treatment of secondary amenorrhea in an efficient, cost-effective, and timely fashion. Categories and compartments have been presented in order to assist one with the myriad of possible diagnostic tests and therapeutic modalities. The etiology and treatment of this common gynecologic symptom is reviewed in order to provide a working knowledge base for the nurse. In addition, the role of the nurse in the care of these clients is explored.
Adolescent↗