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A M Harvey

Publications and source records attributed to A M Harvey.

At least 19 recordsLinked to original sources
PubMed1984

Cecil James Watson.

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History, 20th Century↗
PubMed1983

P22 antirepressor protein prevents in vivo recA-dependent proteolysis of P22 repressor.

A method was developed to demonstrate recA-dependent P22-repressor breakdown in vivo by SDS-polyacrylamide electrophoresis of unfractionated extracts of phage-infected, lysogenic Salmonella typhimurium strains TA1530 rec+ and TA1530 recA1-. The antirepressor of P22 is not cleaved by recA protein. Under conditions of unregulated ant-overproduction (Harvey et al. 1981) antirepressor protects c2-repressor in vivo against proteolytic cleavage by recA protein.

Bacterial Proteins↗
PubMed1979

Repressor synthesis in regulatory mutants of bacteriophage P22.

SDS-polyacrylamide gel analysis of P22-infected Salmonella has allowed identification of the c2 repressor (MW 31,000) and study of repressor synthesis in regulatory mutants of P22. Repressor is synthesized in reduced amounts or is absent in infections with P22, clNo.7, P22, c2 am08, P22 c3 am03, and P22 c3 am012, but is synthesized in markedly increased amounts in the virulent mutant, P22 virB3, and its component mutants, vx and k5. Higher levels of repressor are also found in the P22 cly 17 mutant.

Electrophoresis, Polyacrylamide Gel↗