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Biomedical subjects

A M Kramer

Publications and source records attributed to A M Kramer.

40 records · Page 3Linked to original sources

Stereotypy and hyperactivity in rats receiving ethanol and a monoamine oxidase inhibitor.

The combined administration of tranylcypromine (TCP) and ethanol to rats produced both a marked increase in general locomotion such as walking and running and the appearance of repetitive stereotyped head and trunk weaving, forepaw padding, and circling movements. Pretreatment with p-chlorophenylalanine (pCPA) abolished the stereotyped behaviors. In contrast, animals pretreated with alpha-methyl-p-tyrosine (AMPT) were virtually indistinguishable from those receiving only TCP + ethanol, except for a decrease in running behaviors. The above results are consistent with a serotonergic mediation of these specific stereotypes. The mechanisms by which TCP + ethanol might produce these effects are discussed.

Animals↗

Hospital-based and freestanding home health case mix: implications for medicare reimbursement policy.

This project assessed case mix differences between 299 hospital-based and 354 freestanding clients randomly selected from 20 home health agencies in nine states in 1982. Similarities between hospital-based and freestanding clients outweighed their differences, suggesting that no reimbursement differential is warranted for the two types of providers at this time. Medicare's prospective payment system for hospitals may result in more pronounced case mix differences between the two modalities in the future. Basing payment on case mix is therefore appropriate in order to provide incentives for treating different types of Medicare home health beneficiaries.

Activities of Daily Living↗

A comparison of functional outcomes after hip fracture in group/staff HMOs and fee-for-service systems.

CONTEXT: Previous studies examining differences in the quality of care between capitated and fee-for-service payment systems have focused on the care delivered in a single setting. No study to date has compared outcomes over an entire episode of care delivered across multiple settings. OBJECTIVE: To compare outcomes of care for patients receiving institutional rehabilitation for hip fracture in fee-for-service and group/staff HMO delivery systems. DESIGN: One-year prospective inception cohort. SETTING: Six hospital-based, integrated care systems paid on a traditional fee-for-service model and five group/staff HMOs (paid fixed capitation rate by Medicare). The 11 delivery systems were selected because of their commitment to geriatric rehabilitation. PATIENTS: 196 fee-for-service and 140 group/staff HMO patients with acute hip fracture were identified on admission to inpatient rehabilitation. MEASURES: Four primary outcomes--recovery of activities of daily living, improvement in ambulation, return to community living, and mortality--were measured at 3, 6, 9, and 12 months. Service utilization was assessed in the acute-care hospital setting, rehabilitation setting, and at each 3-month follow-up interval. Risk adjustment was performed by using multiple and logistic regression. RESULTS: Overall, no differences were found between patients in group/staff HMOs and fee-for-service patients. Group/staff HMO patients experienced improved functional recovery at 6 months (P < 0.01) and improved ambulation at 12 months (P = 0.05) compared with fee-for-service patients, although these were isolated findings. With regard to utilization, group/staff HMO delivery systems used physician services less intensively and substituted less-skilled allied health personnel. CONCLUSION: Compared with fee-for-service delivery systems, with a similar commitment to excellence in geriatric rehabilitation, group/staff HMOs can achieve equivalent outcomes in older patients recovering from hip fracture with less-intense service utilization.

Aged↗

Reducing emergency visits in older adults with chronic illness. A randomized, controlled trial of group visits.

CONTEXT: Emergency department utilization by chronically ill older adults may be an important sentinel event signifying a breakdown in care coordination. A primary care group visit (i.e., several patients meeting together with the provider at the same time) may reduce fragmentation of care and subsequent emergency department utilization. OBJECTIVE: To determine whether primary care group visits reduce emergency department utilization in chronically ill older adults. DESIGN: Randomized trial conducted over a 2-year period. SETTING: Group-model HMO in Denver, Colorado. PATIENTS: 295 older adults (> or = 60 years of age) with frequent utilization of outpatient services and one or more chronic illnesses. INTERVENTION: Monthly group visits (generally 8 to 12 patients) with a primary care physician, nurse, and pharmacist held in 19 physician practices. Visits emphasized self-management of chronic illness, peer support, and regular contact with the primary care team. MEASURES: Emergency department visits, hospitalizations, and primary care visits. RESULTS: On average, patients in the intervention group attended 10.6 group visits during the 2-year study period. These patients averaged fewer emergency department visits (0.65 vs. 1.08 visits; P = 0.005) and were less likely to have any emergency department visits (34.9% vs. 52.4%; P = 0.003) than controls. These differences remained statistically significant after controlling for demographic factors, comorbid conditions, functional status, and prior utilization. Adjusted mean difference in visits was -0.42 visits (95% CI, -0.13 to -0.72), and adjusted RR for any emergency department visit was 0.64 (CI, 0.44 to 0.86). CONCLUSION: Monthly group visits reduce emergency department utilization for chronically ill older adults.

Aged↗