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Biomedical subjects

A M Metz

Publications and source records attributed to A M Metz.

15 recordsLinked to original sources
PubMed1992

Isolation and sequence of the cDNAs encoding the subunits of the isozyme form of wheat protein synthesis initiation factor 4F.

The nucleotide sequences of the cDNAs for the two subunits, p82 and p28, of the isozyme form of wheat germ eukaryotic initiation factor 4F (eIF-(iso)4F) were determined. The cDNA for the p82 subunit encodes a polypeptide of 86,514 Da. The deduced amino acid sequence of p82 contains possible motifs for ATP binding, metal binding, and phosphorylation. The cDNA sequence for the small subunit, p28, which is a m7G cap-binding protein, encodes a polypeptide of 23,524 Da. The deduced amino acid sequence of p28 is similar (approximately 38%) to cap-binding proteins from yeast and mammals. The p28 of wheat eIF-(iso)4F does not contain a serine or threonine in the vicinity of the serine (Ser53) of mammalian cap-binding protein which is phosphorylated and shown to affect activity in mammalian cells.

Amino Acid Sequence↗
PubMed1992

Sequence of a cDNA encoding the alpha-subunit of wheat translation elongation factor 1.

A cDNA encoding the alpha-subunit of wheat protein synthesis elongation factor 1 (EF-1 alpha) was isolated from a wheat cDNA expression library and sequenced. The deduced amino acid sequence is compared to EF-1 alpha from other species and to elongation factor Tu (EF-Tu) from Escherichia coli. Putative GTP-binding sites are identified.

Amino Acid Sequence↗
PubMed1992

[The P300 component of the event-related brain potential in a short-term memory paradigm].

In numerous investigations the P300-component of the event-related-brain-potential (ERP) has proved a valid indicator of memory activities. The present study explores the amplitude of the P300 in an isolated short term memory task with variant difficulties. In two experiments the reproduction of senseless memory material was examined using the categories "syllables" and "consonants". One syllable was thereby synonymous with the so-called "chunk" which represents a subjective unit arising from grouping of memory material. The results show a significant increase in P300-amplitude in a line with memory load in both categories. On the contrary there is no significant difference in the amplitude of P300 between the two categories. These results suggest that the costs for storing one syllable are comparable with those for one consonant.

Adult↗
PubMed1990

[The history of the concept stress].

The historical roots of the term are treated as well as the story of Selye's theory of biological stress as a nonspecific response of the body. In the discussion of preceding approaches to describe processes which today one would name stress, the importance of Francois Magendie and John Brown as precursors is accentuated. Additionally, neurophysiological and psychological aspects are discussed.

Animals↗
PubMed1990

[Occupational medicine outpatient management of workers with responsibilities involving great psychological stress].

Some selected results from regular medical occupational fitness evaluations, the statistic of unfitness for work, the disablement of teachers and the occupational referred mortality were demonstrated in special consideration of workers with particular psychic load. From it conclusions were drawn for the development of methods for occupational medical fitness examinations and check ups, prophylactic and therapeutic programmes. The necessarity of scientific dealing with this problems was emphasized.

Adult↗