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A M Molla

Publications and source records attributed to A M Molla.

58 records · Page 4Linked to original sources
PubMedDate not supplied

Maize-salt solution in the treatment of diarrhoea.

In a block-randomized trial we compared the efficacy of citrate-containing glucose electrolyte solution (GES) versus maize-salt solution (MSS) in the treatment of children with mild and moderate diarrhoeal dehydration and acidosis. One hundred and fifteen children aged 3-59 months were entered in the study; 56 received GES and 59 MSS. Fifty-one (91%) of the 56 children given GES and 52 (88%) of the 59 children given MSS were successfully rehydrated with improvement in metabolic acidosis within 24 h. Initial hypokalemia in children treated with maize-salt solution was not corrected during the first 24 h of therapy. The children were, however, clinically asymptomatic after treatment. Carefully prepared maize-salt solution may be used successfully in mild and moderate dehydration in the home, as an alternative to the preferred glucose electrolyte formula.

Bicarbonates↗
PubMedDate not supplied

Effect of antibiotics on food intake and absorption of nutrients for children with diarrhea due to Shigella.

The effect of antibiotic therapy on intake of food and absorption of nutrients for 19 male children aged 1-5 years with suspected shigella infection was studied. The children were admitted to the hospital with acute diarrhea, high fever, abdominal pain, and greater than or equal to 25 red blood cells and white blood cells per high-power field in the stool. Microbiologic diagnosis was made within 48 hours of admission. On the basis of clinical and microbiologic criteria, children were classified as having mild or severe infection. Ten children with mild infection did not receive antibiotics, whereas nine children with severe infection were treated with ampicillin. After the children were rehydrated, a 72-hour balance study was carried out during the acute stage of infection with Shigella and was repeated 2 weeks after recovery. The levels of consumption of food and absorption of nutrients were estimated. During the acute stage of infection, such levels were higher for the children treated with antibiotics than for the untreated group. During the recovery phase, the levels of intake of food and absorption of nutrients were equal for both groups. Thus, children who are treated with appropriate antibiotics not only may recover from infection with Shigella more rapidly, but they also may be able to absorb nutrients more efficiently.

Acute Disease↗
PubMedDate not supplied

Rice-ORS shortens the duration of watery diarrhoeas. Observation from rural Bangladesh.

In rural Bangladesh, standard glucose based oral rehydration salt (glucose-ORS) and rice based oral rehydration salt (rice-ORS) were compared as domiciliary treatment for watery diarrhoea. Using identical supply systems, packaged glucose-ORS was provided in one area and packets of rice-ORS in another. Mothers of under-five children in each area were trained in the preparation and use of the respective ORS. A third area, where no ORS was provided from the study source, served as comparison. In two years of surveillance and follow-up about 10,000 diarrhoeal episodes were detected in each area, approximately one-third of which were watery diarrhoea. Rice-ORS alone was used to treat 74% of these episodes and glucose-ORS alone for 65% of the episodes in the respective areas. Drugs were the main treatment regimen used in the comparison area. Results of the study showed that rice-ORS treated episodes of watery diarrhoea ended with shorter duration (median duration 2 days vs. 4 days) and fewer hospitalisation (0.1% vs. 0.5%) compared to those treated with glucose-ORS. These differences were statistically significant. But, diarrhoeal mortality was unaffected by the use of either ORS under the study situation.

Adolescent↗