Verrucous carcinoma of the penis treated with cryosurgery.
Explore the source record for details and available documents.
Aged↗
Biomedical subjects
A M Moraes
Publications and source records attributed to A M Moraes.
Fungal flora of the digestive tract of 5 species of triatomines vectors of Trypanosoma cruzi, Chagas 1909.
A study of the mycobiota in the digestive tract of 5 important species of triatomines, Triatoma brasiliensis, T infestans, T. sordida, T. pseudomaculata and T. vitticeps, was made. The digestive tracts of 164 adults and 535 nymphs of those triatomines were studied and 393 fungal strains were isolated. The genera with the greatest number of species were Penicillium (19 species), Aspergillus (17 species) and Acremonium (5 species) and the most frequent species, in decreasing order, were Penicillium corylophilum, Aspergillus niger, Penicillium felluttanum, Cladosporium herbarum, Penicillium waksmanii, Aspergillus awamori and Paecilomyces variotii. Among the isolated fungi, we found species that are recognized as entomopathogenic and pathogenic for humans and animals.
Animals↗
Retinal ganglion cells in the South American opossum (Didelphis aurita).
By using the Golgi technique, the authors investigated the morphology of ganglion cells in the retinas of South American opossums. In flat-mount preparations of the retinas, cell bodies, entire dendritic fields, and the stratification level of ganglion cells were studied. Fractal dimensions of dendritic trees, an objective quantitative measure of morphological complexity, were included as a morphological parameter of classification. Based on these characteristics, nineteen types of ganglion cells were described. A great number of opossum ganglion cell types had dendrites stratifying in both sublaminae of the inner plexiform layer (IPL) in five different ways (S1-S3 [G9], S1-S4 [G17 and G22], S2/S3 [G19], S2-S4 [G15, G16, G21 and G221, and S2-S5 [G61), and only two types (G8, and G10) showed narrow field dendritic trees ramifying in S4 only. Morphological types of opossum ganglion cells were compared to their counterparts in cat retina. The distribution pattern of large cell bodies on the ganglion cell layer was analyzed employing the Nissl staining method, immunocytochemistry for neurofilaments, and the reduced silver neurofibrillar staining method. The results showed a random pattern of distribution.
Animals↗
Characterization of coatings for open-heart surgery tubing with heparin and lipid.
The aim of this study was to compare qualitative and quantitative methods for coating characterization on internal surfaces of polyvinyl chloride (PVC) tubing used in procedures of extracorporeal circulation. The methods of characterization included optical microscopy (OM) after dyeing with toluidine blue, scanning electron microscopy (SEM), atomic force microscopy (AFM) and energy dispersive spectrometry (EDS). OM after sample dyeing was excellent in allowing early detection of any absence or irregularities of coatings among the used methods. SEM was the most effective in observing the structure and thickness either in heparin coatings or in lipid coatings. AFM provided a good evaluation of the surface topography. A conjunction of all methods is recommended for complete characterization. The quantification methods based on colorimetric tests were efficient in determining the concentrations of heparin and lipid on internal surface tubes, the coating stability and the reproducibility of the results.
Journal Article↗
Insulin resistance in psoriasis.
The oral glucose tolerance test (OGTT) and intravenous insulin tolerance test (15-min ITT) were applied to ten patients with psoriasis and to 11 control subjects. No significant differences in mean plasma glucose levels were detected between psoriatic patients and normal individuals. In contrast, serum insulin levels were significantly higher for the psoriatic patients as compared to the controls at 30, 60 and 120 min during the OGTT (P < 0.05). The glucose disappearance rate during the 15-min ITT was lower in patients with psoriasis than in controls (5.1 +/- 0.5%/min vs 7.5 +/- 0.4%/min, P < 0.05), demonstrating a state of insulin resistance. Interestingly, the reduction in serum potassium levels during the ITT was also lower in the patients than in the controls (0.6 +/- 0.06 mEq/l vs 1.06 +/- 0.07 mEq/l, P < 0.05), suggesting that the insulin resistance observed in psoriasis is not only related to glucose metabolism, but also to another important action of insulin, namely extrarenal potassium homeostasis.
Adult↗
Beta-like ganglion cells in the South American opossum retina: a Golgi study.
Using the Golgi technique we investigated the morphology of the ganglion cells of the South American opossum retina. We focused our attention on a type of ganglion cell which has a relatively small dendritic field diameter and a medium-sized soma, making it a morphological equivalent of beta ganglion cells of cat retina. Both radial sections of the retina, where the stratification level of ganglion cells dendrites can be observed in the inner plexiform layer (IPL), and flat preparations of the retina, where the whole dendritic field of the ganglion cells can be examined and quantified, have been studied. Usually these cells have one to three primary dendrites, giving rise to short spiny branches. The dendrites of these cells are segregated in two groups, one with dendritic trees arborizing in the inner two thirds and another group arborizing in the outer third of the IPL. The two groups of beta-like cells probably represent the physiological ON- and OFF-center types of ganglion cell as found in cat retina. The mean cell body and dendritic field diameters of 47 cells were 18.5 +/- 1.6 microns, (size range 16-21 microns) and 91.5 +/- 16 microns (range 54-133 microns), respectively. Cell body and dendritic fields sizes were homogeneous across the retina of the opossum. In the opossum the relatively large dendritic fields of the beta-like ganglion cells in the area centralis are consistent with the poor visual acuity of this species.
Animals↗
[Intracoronary thrombolytic therapy: late mortality in 147 patients treated during acute myocardial infarction. Mean follow-up of 13.5 months].
Explore the source record for details and available documents.
Adult↗
[Urinary bacterial levels and urinary leukocyte count and Gram bacterioscopy as indices of infection in normal students of both sexes].
Explore the source record for details and available documents.
Adolescent↗
Preparation and characterization of liposomal systems entrapping the boronated compound o-carboranylpropylamine.
Boron neutron capture therapy (BNCT) is based on the nuclear reaction that occurs when the stable isotope, Boron-10, is irradiated with low-energy thermal neutrons to yield ionizing Helium and Lithium ions that are highly damaging and usually lethal to cells. The successful treatment of cancer by BNCT requires the selective concentration of Boron-10 within malignant tumours. Liposomes have been used as therapeutic compound delivery vehicles for in vivo application, including several anticancer agents. The ability of the boron-containing compound, o-carboranylpropylamine chloride, to accumulate within unilamellar liposomes in response to a transmembrane pH gradient is evaluated. Characterization of the systems obtained is performed for conventional and polyethylene glycol (PEG)-modified (stealth) liposomes, in terms of lipid and CPA contents, vesicle size and stability in detergent solutions. Results demonstrate that CPA loading and vesicle stability can be controlled by the experimental procedure. The loading of CPA into liposomes with average diameters of 100 nm is estimated at 13000 molecules per vesicle for the most stable systems. CPA toxicity to normal human peripheral blood lymphocytes and to adherent glioblastoma multiforme SK-MG-1 cells in vitro is observed to decrease as a result of the entrapment of CPA in liposomes.
Boron Compounds↗