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Biomedical subjects

A M Nogaller

Publications and source records attributed to A M Nogaller.

At least 19 recordsLinked to original sources
PubMed1991

[Immunologic reactivity in patients with food allergy].

One hundred and twenty patients suffering from food allergy were examined for cellular immunity and allergic reactions according to Gell and Coombs. It was found that food allergy was associated most frequently with immediate allergy characterized by elevated blood IgE level and food antibodies titer in the serum. Less frequent were delayed and immunocomplex reactions occurring in severe and polyvalent allergy. In food allergy the count of T-lymphocytes and T-suppressors is reduced, their activity inhibited. There is a moderate rise in B-lymphocytes and T-helpers levels. The treatment promoted improvement of cellular and humoral immunity, though normal indices got recovered in half the cases only. This fact explains frequent recurrences and dictates the necessity of long-term therapy. Elucidation of the mechanisms underlying food allergy may be helpful in administration of valid pathogenetic treatment.

Allergens↗
PubMed1991

[Efficacy of ambulatory treatment of patients with primary chronic gastroduodenitis].

The authors studied the efficacy of the treatment of 80 patients with primary chronic gastroduodenitis on an ambulatory basis. Use was made of spasmolytics, cholinolytics, antacids, sedative agents together with reflexotherapy, dietetic management and physiotherapy. As a result of the treatment, positive changes were recorded in the clinical, functional (intragastric pH-metry with the sodium carbonate test), endoscopic, histomorphologic, morphometric and immunologic characteristics. The changes in the characteristics indicated were examined both shortly after the treatment (1 to 1.5 month) and in the long-term period. Duodenal ulcer developed in 4 persons (5%) in the long-term period, which is 5 times more seldom as compared to the reported data.

Adult↗
PubMed1989

[Treatment of patients with food allergy using Nalcrom].

A total of 65 patients with food allergy which manifested primarily by disorders of the gastrointestinal tract, bronchi and skin were placed under observation. The patients were administered sodium chromoglycate (nalcrom) per os in a dose of 200 mg 4 times a day for 2-3 weeks, in part of cases up to 3 months and even up to 1-1.5 year. The skin manifestations of allergy (pruritus, urticaria, Quincke's edema, and eczematous rash), abdominal pain, diarrhea, vomiting, bronchospasm, rhinitis, and conjunctivitis disappeared. At the same time the majority of the patients demonstrated the reduction of the intensity of skin responses to the administration of different food antigens, the decrease of the antibody titer in blood serum in response to food antigens, and of the IgE content in blood. The side effects (nausea, heartburn, intensification of skin itch and abdominal pain) were noted in 4 cases.

Administration, Oral↗
PubMed1989

[Clinico-immunologic evaluation of the efficacy of bikarfen in allergic dermatoses].

It was found that the new native antihistamine and antiserotonin drug bicarphen possesses in patients with allergic dermatoses (eczema and neurodermatitis) more active antihistaminic, anti-inflammatory, antipruritic and antiallergic properties than commonly used drugs, particularly in cases with prevalence of exudative and allergic reactions of the immediate type. Normalization of rosette-forming T-lymphocytes and A and G immunoglobulins was essential.

Adolescent↗
PubMed1989

[Effectiveness of the treatment of gastric and duodenal ulcers by low-intensity electromagnetic (laser) radiation].

The effectiveness of treatment of ulcer patients with various types of laser radiation by the argon, heliun-neon and crypton lasers was studied in 137 patients. The results of laser treatment were compared with those in controls constituting 60 patients who were treated with commonly used therapeutic methods. The sparing techniques of laser therapy promote much earlier cicatrization of gastric and duodenal ulcers, shorter terms of hospital stay and reduction of temporary working disability. Laser therapy leads to a decrease in the number of disease recurrences in the first two months and has no significant influence on the incidence of recurrences in the remote period.

Duodenoscopy↗
PubMed1987

[Diagnostic significance of the determination of IgE in food allergy].

The total level of IgE was determined in 84 patients with food allergy and in 19 healthy individuals. The level of IgE was significantly elevated in food allergy reflecting a degree of body sensitization. The absence of complete correlation between the clinical signs of disease and the blood level of IgE could depend upon the involvement of IgG-mediated allergic reactions in the pathogenesis of disease. Specific antibodies to ovalbumin of the IgG class were detected in 18 of 25 patients. Certain correlation between a therapeutic clinical effect and the time course of the serum level of IgE was observed.

Adolescent↗