[Correction of hemodynamics in elderly and aged patients after bile duct operation].
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Biomedical subjects
Publications and source records attributed to A M Ovezov.
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Thirty patients from 3 groups that differed only in the scope of monitoring were examined to study the efficiency of combined neurophysiological and autonomic nervous monitoring in the assess of the quality of anesthesiological protection during highly traumatic surgical interventions made in abdominal patients under combined general anesthesia based on long-term graded epidural naropine (3 mg/ml) infusion at the thoracic level Addition of the Harvard standard with monitoring the information saturation of EEG made it possible to maintain the depth of anesthesia, by reducing the dose of dormicum by 20% (p < 0.05). The use of combined monitoring of EEG information saturation and the tension index after R. M. Bayevsky could reduce the dose of fentanyl by 2.3-2.7 times (p < 0.05) and the incidence of critical cardiovascular incidents by 39% (p < 0.05).
Sixty-nine patients from 2 groups were examined to optimize anesthesiological support of highly traumatic abdominal interventions. Whether graded prolonged epidural infusion of 0.3% naropine solution could be combined with low-flow anesthesia with isoflurane and oxide-oxygen mixture, which could ensure adequate actinociception and completely refuse narcotic analgesics, was studied. The proposed type of combined inhalation-epidural anesthesia creates favorable conditions for the cardiovascular system to function, by increasing cardiac output by 25-30%, by lowering postload by 16% and heart rate by 11-17% with the stability of the remaining central hemodynamic parameters, provides a significant depth of anesthesia and a sufficient stability of regulatory systems and homeostasis during highly traumatic abdominal operations.
The purpose of this study was to examine the expediency and efficiency of use of an infusion administration of naropine into the epidural space for intraoperative anesthesia and to develop the optimum procedure for administering this anesthetic during operations on the upper abdomen. Studies were performed in 43 patients operated on for different pancreatic diseases. Anesthesia based on epidural naropine infusion versus ataralgesia was compared. This study indicated that epidural naropine infusion-based anesthesia provides stable hemodynamic parameters and reduces the use of narcotic analgesics by more than twice. Inclusion of prolonged epidural infusion of 0.3% naropine solution into the anesthesiological appliance scheme during this type of operations provides an adequate antinociceptive protection and contributes to the early activation of patients, which prevents the development of postoperative complications.
A comparative analysis of blood oxygen-transportingfunction (BOTF) under 6 types of combined general anesthesia (low-flow inhalational anesthesia in combination with a narcotic analgesic or with continuous graded epidural infusion (CGEI) of local anesthetics) during high-traumatic and prolonged operations on the hepatopancreaoduodenal area has revealed no significant abnormalities of tissue oxygen transport and metabolism. At the same time when a procedure of anesthesia is chosen for this category of patients, preference should be given to a combination of CGEI and low-flow inhalational anesthesia with isoflurane in nitrous-oxide mixture, which provides a minimum drug load, optimal conditionsfor cardiovascular performance, and stability of BOTF parameters even in baseline endotoxicosis.