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Biomedical subjects

A M Picard

Publications and source records attributed to A M Picard.

3 recordsLinked to original sources

Neuroleptanesthesia versus thoracic epidural anesthesia for abdominal aortic surgery.

The hemodynamic consequences of abdominal aortic surgery with infrarenal cross-clamping were studied in 21 patients randomized in two groups. In Group I (11 patients), neuroleptanesthesia was utilized, while Group II (10 patients) received thoracic epidural anesthesia at the T8-9 level. Hemodynamic measurements were performed using Swan-Ganz catheters during the surgical procedures in all patients, with special attention to the periods of clamping and unclamping of the abdominal aorta. The thoracic epidural anesthesia group was characterized by greater hemodynamic stability during surgery, while patients in the neuroleptanesthesia group had significant lability of blood pressure, heart rate, and cardiac index. Nevertheless, in the two groups of patients, it is suggested that cardiac function was unfitted to the tissue oxygen demand after unclamping of the aortic prosthesis because the saturation in oxygen of the mixed venous blood and an increase in arteriovenous difference in oxygen were documented. These results point out that, whatever the anesthesia technique, the critical period in abdominal surgery could be aortic unclamping.

Anesthesia, Epidural↗

[Partial trisomy for the distal part of the short arm of chromosome 11 due to paternal translocations 11/5].

A girl with partial trisomy for the short arm of chromosome 11 resulting from an unbalanced translocation 46,XX,der 5, t(5,11) (p 15,p14) pat is described. The clinical findings are compared with those of other patients with partial trisomy 11p. The translocation in the balanced form was present in the fater, the brother, and the grandmother of the proposita.

Abnormalities, Multiple↗

[Partial trisomy 11 revealed by labeling technics].

A standard karyotype was normal in 1968, when performed in a girl with multiple malformations. The same investigation was performed 7 years later with labelling techniques. It showed a partial duplication of the short arm of chromosome no. 11. This emphasizes the interest of a second karyotype in clinically suggestive cases, if the first has been performed before labelling techniques were used.

Abnormalities, Multiple↗