Denatured alcohol is not toxic for the eye.
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Biomedical subjects
Publications and source records attributed to A M Potts.
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We have reported two cases of keratopathy in polyurethane workers that appear to be identical to those described by previous authors. We have been able to produce similar findings in the corneas of cats by exposing the eyes of anesthetized animals to the vapor of two of the amines used as catalysts in polyurethane manufacture. We were unable to reproduce these results with toluene diisocyanate. Therefore we support the previous suggestion that the amine catalysts are responsible for the distinctive keratopathy in polyurethane workers. We are unable to substantiate the claim that toluene diisocyanate is responsible for this phenomenon.
We studied the way in which the shape of a missile striking the eye affects the ease of penetration of the central cornea. The test objects were enucleated pigs' eyes restored to normal intraocular pressure by cannulation of the optic nerve and connection of the cannula to a manometric system of physiologic saline. The shape, size, and weight of the missiles were carefully controlled. We attempted to keep these factors within the range of common civilian experience. Missile speed was measured photoelectrically. For each combination of weight and velocity, penetration of the missile was determined consistently, by the point shape. Penetration was most difficult for the blunt tip and least difficult for the knife-shaped tip.
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In this study I dealt with two principal aspects of the seemingly irrational subject of chronic open-angle glaucoma: surgery for chronic open-angle glaucoma, and the unique pattern of damage encountered in chronic open-angle glaucoma. Available surgical procedures were treated as a continuous series, depending on the amount of pressure-lowering expected. Vascular interaction was hypothesized to explain the typical pattern of damage.
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As a first step toward determining the source of variability in the visually evoked response (VER) between subjects, we have examined the relationships between the VER and the alpha-rhythm. This was done by comparing the VER's to photic stimuli delivered at positive and negative peaks of the alpha-rhythm (alpha-synchronized stimuli) with VER's to flashes delivered at a fixed interval, unsynchronized with the alpha-rhythm. Average VER's for the three classes of stimuli were calcuated for each of ten subjects. In addition, a grand average VER (GVVER) WAS CALCULATED FOR EACH STIMULUS CLASS BY AVERAGING THE INDIVIDUAL AVERAGE VER's. Quantitative comparisons between GVER's were made using cross- correlograms. Cross-correlograms were calculated between each of the GVER's, and between the GVER's to alpha-synchronized stimulation and their controls. These data show that the first 120 msec. poststimulus interval of the Gver's to alpha-synchronized stimulation are highly correlated with the prestimulus alpha- rhythm. The data also show a component occurring in al GVER's which is independent of the alpha-rhythm. This component begins 120 msec. After stimulation, reaches peak amplitude at 200 msec, and decays to baseline at 240 msec. Thses findings suggest that much of the variability in VER recordings may be due to alpha-activity which has been insufficiently attenuated by averaging.
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