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Biomedical subjects

A M Sedlaczek

Publications and source records attributed to A M Sedlaczek.

14 recordsLinked to original sources

[The time necessary for establishing a morphological diagnosis in patients with inoperable lung cancer].

The authors analyze the time period necessary for morphological diagnosis in 100 consecutive patients with inoperable lung cancer admitted for treatment to the Department of pulmonology and tuberculosis of the Szczecin Medical Academy from 1989 through 1990. The following methods were used: cytological examination of sputum, bronchoscopy, fiber bronchoscopy, transthoracic biopsy by a thin needle, biopsy of the metastatic focus and cytological examination of the pleural cavity fluid. The causes of inoperability were: tumour histobiology variants (anaplastic small-cell cancer), cardiovascular failure and technical in operability. The diagnosis was established in all patients averagely within 16 days of hospital stay. More frequently the diagnostic material was obtained by means of bronchoscopy, then cytological examination of the sputum and transthoracic biopsy. In some patients without symptoms it is expedient to carry out diagnostic procedures in outpatient condition which is of economic importance.

Adult

[A case of endobronchial hamartoma].

A case of an endobronchial hamartoma localized in the right basal bronchus is presented. The tumor was ablated bronchoscopically. Due to uncertainty of total excision and coexistence of cirrhotic changes of the right lower lobe surgical removal of the lobe was carried out. Pathological examination of the removed specimen did not disclose any remnants of the hamartoma. During surgery another growth anomaly was discovered--a bilobar right lung.

Bronchography

[Comparative assessment of the theoretical values of vital capacity (VC) considered normal by various authors].

Values of VC for "theoretical subjects" of comparable sexes, age, height were found in tables and normograms according to Baldwin, Berglund, Kory, Nikodemowicz and Morris. For each series of values, mean, standard deviation, minimal, maximal, and median values were calculated. A differential test was performed to assess significance. Statistically significant differences were found. The highest values were expressed by Morris lowest by Berglund. It seems that one should rather use real values instead of predicted and new reference values are needed due to a change of height-age relation during the past 20 years.

Adult

[Analysis of the clinical course of occupational pulmonary tuberculosis in medical personnel of the Western Pomerania macroregion 1978-1987].

An analysis of the clinical course of pulmonary tuberculosis diagnosed in medical personal of the Western Pomeranian macroregion in the years 1978-1987 was carried out. Most often nurses develop this disease followed by technicians and doctors. 43% of this population did not have constant contact with active tuberculosis. Symptoms led to a diagnosis in 40% of the cases. In 27 patients radiological changes involved less than two pulmonary fields. In 17 cases a three drug regimen was instituted. The average hospitalization period was lower in these cases than in other treated in this region. Also the incidence rates of at risk medical personal were lower than overal incidence rates.

Adult

[Analysis of the clinical course of pulmonary tuberculosis in women over 70 years of age].

The course of pulmonary tuberculosis was analyzed in 34 females older than 70 years and 30 women, age range 35-55 years (mean 43.8 yrs) treated between 1.01.1985 and 31.12.1988 in the Pulmonological Department of the Szczecin Medical Academy. Pulmonary tuberculosis in females aged more than 70 years was diagnosed basing mainly on clinical grounds (82%), positive sputum (88%) and advanced radiological changes. In 25% evidence of the middle lobe syndrome was found--all sputum positive. In the control group such findings were not seen. In almost all patients of this group 4 drug therapy was instituted. Streptomycin was tolerated the poorest. The therapeutical course was similar in both groups. Pulmonary tuberculosis in the studied group was usually diagnosed in the advanced stage. The population of females of 70 years and older is an important epidemiological risk factor.

Age Factors

[Comparative analysis of basic spirometric parameters recognized by different authors as normal values for the same individuals].

Basic spirometric parameters (VC, FEV1, MVV) were recorded in 60 people (30 males and 30 females) without ventilatory disturbances. These results were compared with the normal values of Berglund, Kory, Cournand, Morris and Nikodemowicz. A statistical analysis was carried out using the differential test. The results differed significantly between each other. The most stable parameter that did not differ was FEV1. This may be an argument for calculating IMBC rather than recording maximal ventilatory response.

Adult