[Erosive lesions of the gastric mucosa in chronic renal failure].
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Adolescent↗
Biomedical subjects
A M Shutov
Publications and source records attributed to A M Shutov.
[Effect of acute normobaric hypoxia on electrical stability of the myocardium in healthy people].
We studied the impact of acute 10-min normobaric hypoxia on myocardial electrical stability, systolic and diastolic cardiac functions in 10 young healthy men. Hypoxia induced a decrease of ejection fraction and left ventricular early peak filling velocity. The QTc interval was prolonged during normobaric hypoxia without QT dispersion increase. Electrocardiographic investigation with assessment of QT-interval must be mandatory before normobaric hypoxic therapy is started. Prolonged QT interval is contraindication to normobaric hypoxic therapy.
Adolescent↗
[Dehydroepiandrosterone and sexual function in men with chronic prostatitis].
The aim of this study was to determine relationships between the level of DHEA-sulfate (DHEA-S), an erectile function and libido in men with chronic prostatitis. 53 patients (mean age 44.6 +/- 12.0; range 21-68 years) with chronic prostatitis were studied. Libido and erection were estimated and patients were divided into two groups according to their sexual dysfunction: 21 patients with severe sexual dysfunction (SSD) and 32 patients with mild sexual dysfunction (MSD). Testosterone, prolactin and DHEA-S were detected by ELISA. SSD patients had a lower testosterone level than patients with MSD (11.8 +/- 4.6 vs 14.8 +/- 5.9 nmol/l, respectively, p = 0.04) and DHEA-S (1.7 +/- 0.8 vs 2.5 +/- 1.2 microg/ml, respectively, p = 0.01). There was a negative correlation between the age of the patients and an erectile function (r = -0.70; p < 0.001), age and libido (r = -0.57; p < 0.001). The negative correlation was revealed between DHEA-S and age (r = -0.59; p < 0.001). A positive correlation was between DHEA-S and an erectile function (r = 0.45, p = 0.001). There was no correlation between DHEA-S and serum testosterone level (r = 0.10; p = 0.5). Multiple regression analysis showed an independent positive correlation between DHEA-S and erectile function in patients with chronic prostatitis (beta = 0.28; p = 0.02; R2 = 0.40). The findings show that erectile dysfunction independently from age is associated with a lower level of serum DHEA-S in patients with chronic prostatitis.
Adult↗
[The effect of erythropoetin on doxorubicin-induced oxidative stress in rat kidney].
The early nephrotoxicity manifestations (oxidative stress) caused by a single administration of doxorubicin in rats and the therapeutic effect of erythropoietin have been studied. The introduction of doxorubicin leads to a decrease in the concentration of glutathione and the activity of glutathione reductase in rat kidneys, which is indicative of the development of oxidative stress. Erythropoietin restores glutathione content on the normal level. The pretreatment with erythropoietin reduces the doxorubicin induced damage in rat kidneys.
Animals↗
[Value of the antibody-coated bacteria test in the diagnosis of chronic pyelonephritis].
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Adolescent↗
[The serological diagnosis of hemorrhagic fever with renal syndrome].
Early serological diagnosis of hemorrhagic fever with renal syndrome (HFRS) in 45 patients did not affect survival and policy of hemodialysis. However, the number of procedures, invasive in particular, to verify the diagnosis was much less. Perfection of HFRS early diagnosis promotes optimization of the disease detection.
Acute Disease↗
[The evaluation of the detoxication function of the kidneys by the clearance of middle molecules].
The detoxifying function of the kidneys was examined in 56 patients with renal diseases. The function was assessed from the clearance of medium-mass molecules in relation to the total water content in the body. Medium-mass molecules in the serum and urine were assessed by the method based on direct UV spectrophotometry. A correlation has been revealed between the content of medium-mass molecules, serum creatinine, clearance of creatinine, and the detoxifying function of the kidneys. The method is simple, reliable, and does not require expensive reagents.
Adolescent↗