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Biomedical subjects

A M Sur

Publications and source records attributed to A M Sur.

13 recordsLinked to original sources

Comparative evaluation of two maternal weight-height indices during pregnancy.

Three hundred forty one primiparous women and their offsprings were the subjects of the study. Mothers were subjected to weight and height measurement as well as hemoglobin estimation. The weight for height ratio index (WHRI) and weight-height product index (WHPI) were calculated. Both WHRI and WHPI were studied in relation to birth weight (BW). WHPI was found to be superior over WHRI as it explained greater per cent variation in birth weight. The means for BW increased and incidence of low birth weight babies decreased significantly with increase of WHPI in each WHRI group.

Birth Weight

Iron deficiency in sicle cell disease.

Iron studies were performed on 25 children with homozygous sickle cell disease. The majority (80%) of patients had never been transfused. Surprisingly, the results showed that all had low serum iron and low transferrin saturation. Three children had no marrow iron stores while the rest had diminished amounts of iron. This may be an important finding in view of recent efforts at fortifying common salt with iron. The exact effects of iron deficiency on sickle cell disease are not known and a controlled trial is called for.

Adolescent

Indian childhood cirrhosis: an inherited disorder of tryptophan metabolism?

Urine samples from members of 29 families of patients with Indian childhood cirrhosis (ICC) and nine families with related disorders gave positive reactions when tested with ferric chloride. Column chromatography showed that this was due to the presence of abnormally large amounts of tryptophan metabolites, notably 3-hydroxyanthranilic acid. Affected pedigrees had a significantly greater prevalence of peptic ulcer, adult cirrhosis, diabetes mellitus, migraine, and Parkinsonism than a control population. ICC may result from an inborn error of tryptophan metabolism in susceptible ethnic groups.

Adult