Biomedical subjects
A M Voda
Publications and source records attributed to A M Voda.
The confusion in obesity research standards.
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Seasonal characteristics of and age at menarche.
Data from approximately 600 U.S. women were analyzed for seasonality in menarche. Data were converted to the ratio of observed (O) to expected (E) cases, based on an equal distribution of events over the year, per considered time span of the year. The greatest O/E ratio in menarche (1.55) occurred during January, followed by August (1.43) and July (1.24). The lowest O/E ratio in menarche occurred in February and May (0.68). Seasonal patterns in menarche were detected for the separate cohorts of women born during the 1940s, 1950s, and 1960s, with a shift from a December-January peak in menarche for those born in the 1940s and 1950s to an August-September peak for those born in the 1960s. Girls who were younger (8-14 yrs) at menarche exhibited a seasonal difference in the peak number of menarches by about 6 months in comparison to the pattern for girls who were older (15-17 yrs). Girls who experienced menarche during August-October were statistically significantly younger (p less than 0.05) than those born during the other three seasons. Season of birth was not statistically significantly associated with season of menarche. Overall, no 12-month pattern was substantiated by cosinor analysis in the month of menarche. However, a 6-month rhythm was detected in menarche for women born between 1940 and 1960 (p = 0.004, A = 29% M, phi = January and July).
Seasonal characteristics of and age at menarche.
Several patterns in menarche are evident over time and across populations which vary by ethnicity, socioeconomic status and altitude of residence: peak occurrence of menarche in January and August with a possible minor peak in April; troughs in the occurrence of menarche to either side of the peak months; and secular trends in season and age patterns of menarche. Contradictory patterns in season of menarche with respect to age at menarche and season of menarche with respect to season of birth are still unresolved. Further research is yet required to evaluate the role of the variety of endogenous and exogenous variables and their interactions on menarche in order to more fully develop an appropriate understanding of the chronobiology of developmental and reproductive phenomena in women and their dependence upon environmental quality and temporal cues.
Temporal patterns of hot flashes in natural and surgically-induced menopause.
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Circadian rhythms in hot flashes in natural and surgically-induced menopause.
The aim of this study was to investigate circadian and ultradian variations in menopausal hot flash. The number of hot flashes per 2-hr period was collected from 25 diurnally-active, perimenopausal women for 1 week in January or February of each year for 3 consecutive years. Fourteen women were experiencing natural menopause (NM) (mean age 51.9 years) and 11 were experiencing surgically-induced menopause (SIM) (mean age 52.0 years). The difference in the number of hot flashes between the two types of menopause at each clock time was not statistically significant; neither was the mean number of hot flashes per 24 hr different between the two groups (Student's t-test). Data when normalized for each woman and placed end-to-end revealed by cosinor analysis circadian rhythmicity in the SIM group (P = 0.02) but not in the NM group. A 12-hr periodicity was detected in both groups (P less than 0.001 for both). An 8-hr rhythm was detected only for the NM group (P = 0.04). Both groups combined exhibited statistically significant rhythmicities with periods of 24 hr (P = 0.003), 12 hr (P less than 0.001) and 8 hr (P = 0.005). Regardless of the type of menopause, the women could be separated into two groups based on the temporal pattern of hot flashes during the day. One group was defined by the occurrence of peak frequency of flashes during the morning (0400-0959), while the second group was defined by the occurrence of the peak in the evening (1600-2159).(ABSTRACT TRUNCATED AT 250 WORDS)
Menopausal hot flashes and osteoporosis.
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Research on nursing practice. Menopause.
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Body water dynamics. A clinical application.
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Laminar airflow in the OR.
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Menopause: the closure of menstrual life.
This paper discusses questions frequently asked by menopausal women regarding body and affective changes associated with the menopause. Menopause as disease is contrasted with menopause as normal. Common menopausal changes and ways in which to deal with them are presented. Answers to some of the questions and concerns that women have cannot be found in the research done to date because of lack of unbiased research on the normalcy of menopause. Thus, this paper illustrates the need for woman-centered research to answer women-related phenomena.
On the process of involving nurses in research.
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