PubMed Health⌕ Search

Biomedical subjects

A M el-Naggar

Publications and source records attributed to A M el-Naggar.

At least 19 recordsLinked to original sources
PubMed1986

Synthesis of some 1-acetylindoline-5-sulphonylamino acid derivatives and studies of their antimicrobial activities.

The synthesis of a series of 1-acetylindoline-5-sulphonylamino acids and some of the corresponding methyl esters and hydrazides (II-XXIII) is described. Coupling of 1-acetylindoline-5-sulphonylamino acids with amino acid methyl ester hydrochlorides in THF-Et3N medium, using the dicyclohexylcarbodiimide method gave the desired 1-acetylindoline-5-sulphonyldipeptide methyl esters (XXIV-XXVIII). Most of the synthetic 1-acetylindoline-5-sulphonylamino acid and dipeptide derivatives (II-XXVII) were found to possess various antimicrobial activities against a number of microorganisms.

Amino Acids↗
PubMed1985

Synthesis and antimicrobial activity of some new isonicotinoylamino acid and dipeptide derivatives.

The synthesis of a series of isonicotinoylamino acids (II-XI) and some of their corresponding methyl esters (XII-XVIII), hydrazides (XXI-XXVI), dipeptide methyl esters (XXVII-XLII), the di- and tri-glycine peptides (XIX-XX) is described. Sixteen of various isonicotinoylamino acid and dipeptide derivatives were found to possess specific antimicrobial activities towards different microorganisms.

Amino Acid Sequence↗
PubMed1985

Synthesis of some isonicotinoyl- and nicotinoyl-sulphonylamino acid derivatives and their antimicrobial activity.

The synthesis of isonicotinoylamino acids-2-sulphonylamino acids and nicotinoylamino acids-5-sulphonylamino acids (III-VII) and (XXIII-XXVII) and their corresponding methyl esters, hydrazides and some dipeptide methyl ester derivatives (VII-XXII) and (XXVIII-XXXVII) are described. Thirty two of various substituted nicotinoyl and isonicotinoyl sulphonylamino acid derivatives were found to possess specific antimicrobial activities towards different microorganisms.

Amino Acids↗
PubMed1984

Biologically active halophthaloylpeptides. I. Synthesis of tetrachlorophthaloylamino acids and dipeptide derivatives.

The synthesis of a series of tetrachlorophthaloylamino acids and some of the corresponding methyl esters is described. Coupling of tetrachlorophthaloylamino acids with amino acid methyl esters by the N,N'-dicyclohexylcarbodiimide method yielded the desired tetrachlorophthaloyldipeptide methyl esters. All of the synthesized tetrachlorophthaloylamino acids, esters and some dipeptide methyl esters were found to be active against a number of microorganisms.

Anti-Bacterial Agents↗