[Familial juvenile nephronophthisis].
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Biomedical subjects
Publications and source records attributed to A Maccioni.
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277 patients subjected to phlebography for clinically suspect acute deep venous thrombosis of the lower extremities have been examined. Instrumental examination evidenced the presence of thrombosis in 140 of them (50.5%) while in the remaining 137 (49.5%) in whom venography proved negative, it was possible to define the pathologies responsible for the clinical picture in 89% of cases. In out-patients, the incidence of thrombosis proved lower (46%, 65/141 patients) than that presented by patients already hospitalised for other pathologies (55%, 75/136 patients). No significant differences were observed in the incidence of clinical symptoms and signs between patients with thrombosis and patients without at phlebography, while as regards the distribution of risk factors, there was a greater incidence of the following: age over-65, cancers, recent surgery and fractures of the lower extremities in the group of patients suffering from thrombosis. Personal experience would therefore appear to point to the total fallibility of the clinical diagnosis of deep venous thrombosis of the lower extremities and the consequent need for a constant objective instrumental diagnostic approach to this type of pathology.
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