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Biomedical subjects

A Magherini

Publications and source records attributed to A Magherini.

At least 37 records · Page 2Linked to original sources

Pulsed Doppler echocardiography for diagnosis of ventricular septal defects.

In order to assess the performance of pulsed Doppler echocardiography and to examine the factors affecting its reliability for the diagnosis of ventricular septal defects, 51 patients, in whom angiographic studies had recently been performed, were investigated before and after operation by this technique. The diagnosis was correct in all cases with left-to-right shunt, when the defect was located either in the upper muscular or in the infracristal portion of the septum, even when pulmonary hypertension or additional cardiac malformations were present. Pulsed Doppler echocardiography did not differentiate between supracristal ventricular septal defects and obstruction of the right ventricular outflow. Apical muscular defects were never observed in our cases. Defects of the inlet portion were not localised by the method. In cases with bidirectional shunt, pulsed Doppler echocardiography failed to provide any diagnostic clue. When a right-to-left shunt was present, only in one case with membranous pseudoaneurysm could pulsed Doppler echocardiography provide an exact description of the haemodynamics before and after operation. In 12 of 22 patients with tetralogy of Fallot, pulsed Doppler echocardiography showed flow tracings possibly related to the septal defect. The site of defect and the extent and direction of intracardiac shunting seem to be the main factors affecting its diagnostic performance in ventricular septal defects.

Doppler Effect↗

[Carcinoid heart disease. Report of a case (author's transl)].

A case of carcinoid tumor characterized by isolated tricuspid insufficiency with stenosis is reported. This valvular disease was characterized by a slight increase of cardiac output and pulmonary pressures. Necropsy did not evidence the site of the primitive tumor. Tricuspid valve lumen was near normal while the pulmonary valve presented slight stenosis. The correlations between clinical feature and necroscopic findings are discussed.

Autopsy↗

[Bidimensional echocardiography for pre- and post-surgical evaluation of atrio-ventricular canal defects (author's transl)].

Bidimensional echocardiography was employed for pre- and post-surgical evaluation of patients with Atrio-Ventricular Canal (AVC) defects. In 14 of the total 24 patients the echocardiographic images were compared with the actual anatomy at surgical inspection. In all cases bidimensional investigations provided essential clues toward diagnosis of AVC demonstrating the peculiar anatomic disorders (ostium primum, cleft anterior mitral cusp, anomalies of the left ventricular outflow tract). Moreover it made possible to distinguish between partial and complete forms of AVC demonstrating the degree of septal development and, where it present at the level of the interventricular septum, to show the split of the anterior cusp of the common AV valve into a mitral and tricuspidal components. In postoperative evaluations could be clearly visualized the following: the prosthetic patches, the thickened mitral anterior cusp (an indirect image of the sutured cleft) and, in the complete forms, the newly formed individual valvular ostia. Bidimensional echocardiography improved greatly the performance of ultra-sound investigation for patients with AVC.

Adolescent↗

[Two-dimensional echocardiography to evaluate anomalies of the great arteries (author's transl)].

Two dimensional Echocardiography was employed to study 51 subjects with complex anomalies of the great arteries. Within a short period of time, they underwent also angiographic investigations and corrective surgery. The investigation was performed orienting the transducer according to two approaches. --Short-axis view: at the level of the origin of the great arteries, and from the basis of the ventricular septum. --Long-axis view: along the longitudinal axis of the heart. In all cases two dimensional Echocardiography could clarify the mutual interrelation of the great arteries, according to the classification by de La Cruz, and the relation between the great arteries and the ventricular septum. Only in two cases, where the dimensions of the ventricular septal defect were particularly large, the position of the great arteries relative to the septum itself could not be assessed.

Echocardiography↗

[Dynamic geometry of the left ventricle. Relaxation and elasticity indices].

A study was made of 34 patients with valve defects or arterial hypertension and a haemodynamic picture of left ventricle pressure or volume load. Echocardiography and haemodynamic investigated-established the size and mass of the left ventricle and also enabled its indices of contractility, relaxation and distensibility to be determined. The series was divided in accordance with the dynamic geometry of the left ventricle. In concentric hypertrophy, telediastolic rigidity increased in proportion to ventricular thickness and mass. In eccentric forms and ventricular dilatation, diastolic distensibility was reduced in cases with a high filling pressure. The relaxation values bore no relationship to distensibility and telediastolic compliance. The relaxation rate in protodiastole diminishes in proportion to functional depression of the left ventricle.

Cardiac Catheterization↗

[The Doppler-echocardiography in the study of transvalvular pulmonary flow (author's transl)].

The AA. studied 96 subjects: 74 normals, 15 patients with pulmonary stenosis, 6 with pulmonary regurgitation and 1 with combined stenosis and pulmonary regurgitation, by using pulsed Doppler echocardiography. This technique, which supplements M-mode echocardiography with Doppler flow detection, allowed determination of direction and quality--laminar or turbolent--of flow through pulmonary valve. In our experience, pulsed Doppler echocardiography is a sensitive and specific method for detection of pulmonary stenosis and regurgitation and extends ultrasound diagnosis beyond the capabilities of M-mode echocardiography.

Blood Flow Velocity↗

[Doppler echocardiography in the diagnosis of tricuspid anomalies (author's transl)].

Doppler echocardiography has been applied in a study of the tricuspid and central venous blood velocity curves in a number of cases, including eleven cases of insufficiency, six cases of stenosis, five cases of steno-insufficiency of the tricuspid valve and one case of Ebstein's disease. The tracings were compared to normal reports and to those appartaining to a few patients with right ventricular failure from different causes. For six patients the venous blood velocity curve was recorded contemporaneously with the right atrioventricular pressure curves. Doppler echocardiography has proved that it can offer useful indications on tricuspid anomalies. The analysis of the central venous and tricuspid blood velocity curve allows us to detect hemodynamic alterations characteristic of this valvular disease.

Blood Flow Velocity↗