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Biomedical subjects

A Makowski

Publications and source records attributed to A Makowski.

At least 19 recordsLinked to original sources

[Minor congenital ear malformations: surgical management and results].

The study present the results of surgical treatment of minor congenital anomalies of the middle ear in children. The ossiculoplastic procedures and the different types of stapedectomy carried out in the Department of Otolaryngology of Institute of the "Polish Mother's Hospital" in Łódź on 18 patients (11 girls and 7 boys) aged 5-16 years, with minor congenital anomalies of the middle ear. One month after the surgical procedure a lasting hearing improvement averaging 21.69 +/- 10.00 dB and 6 month after operation hearing improvement 21.91 +/- 9.75 dB was gained. The results of surgical procedures in minor congenital anomalies of the middle ear are not so good as in otosclerosis.

Adolescent↗

[pH of fluid collected from middle ear in the course of otitis media in children].

In course of the study, pH of secretions taken during operation from middle ear of 112 children suffering OMS was examined. Samples of serous, mucous and serous-mucous secretions were collected. Values of pH were determined using 6.4-8.0 and 8.2-10.0 test-papers produced by E. Merck. pH of all samples was alkaline. Mean value of pH of mucous and serous-mucous secretion was higher (8.55 and 8.33, respectively), than serous secretion (7.92). Positive correlation between the age of children and pH of secretions was noticed.

Child↗

[Cytological picture of fluid collected from middle ear in course of o.m.s. in children].

The fluid collected during operation from tympanic cavity of 37 children with o.m.s. was examined. Its cellular composition was assessed by microscopic observation in magnification of 400 in 10 different fields of view. Lymphocytes, neutrophiles, eosinophiles and macrophages were counted. The ratio of number of macrophages to the total number of lymphocytes granulocytes was expressed in percent. The concentration of proteins was evaluated using stripe method Multistix 10 SG and comparatively, after staining the fixed preparation with hematoxylin and eosine, on the basis of pink colour, which intensity is proportional to the amount of protein. The exudative fluid was found to be protein-rich; it contained numerous lymphocytes in 56% of samples; epithelioid cells were sparse or absent in 53% of samples; in 95% of samples eosinophiles were absent, or occurred in small numbers, in 65% of samples only few neutrophiles was found. The fraction of immature cells in total number of neutrophiles decreased evidently with increase of this number (r2 = 0.85); the average ratio of the number of macrophages to the total number of lymphocytes and granulocytes was 32%. The relationship between hypoacusia and cytological parameters of ear secretion was analysed. It was discovered, that there was no dependence between the value of hypoacusia and the concentration of proteins, neither the total number of cells in fluid. With the increase of hypoacusia, the number of eosinophiles decreased. Further studies are required to check whether hypoacusia is dependent on the amount of secretion.

Child↗

[Bacteriologic evaluation of middle ear fluid during the course of secretory otitis media in children].

Fluid collected from tympanic cavity during operation from 43 children with O.M.S. was subjected to bacteriological examination. After the collection, each sample was immediately applied to Bactec Peds Plus/F liquid medium from Becton Dickinson. The number of samples, where each genus and species of bacteria were found, was determined, as well as the number of samples where every two genus coexisted; also the pH genes, in which each genus was found were calculated. Obtained results showed that 22 species of bacteria, belonging to 6 genus lived in the samples. The most commonly occurring genus were Staphylococcus, Streptococcus and Haemophilus; the most rare genus were Moraxella and Bacillus. The most common species were: Haemophilus influenzae (18.6% of samples), Staphylococcus aureus (14.0%), Staphylococcus epidermidis (11.6%), Staphylococcus warneri (9.3%) and Streptococcus oralis (7.0%). Streptococcus coexisted most frequently with Staphylococcus and Haemophilus; Staphylococcus--with Haemophilus and Bacillus; Haemophilus--with Streptococcus and Staphylococcus. The pH ranges for the three most often found genus were: for Staphylococcus--7.7-9, for Streptococcus--7.7-9.3 and for Haemophilus--8.2-8.8.

Bacillus↗

[Results of the surgical management of congenital malformations of the external auditory canal and of the middle ear in children with special reference to vein xenografts].

The paper deals with the possibility of surgical reconstruction of congenital malformations of the ear, the choice of a proper surgical method with the utilization of calf-vein xenografts, and with postoperative effects of the employed operative technique modified by the authors. The research material comprised 70 children between 3 and 17 years of age treated in years 1992-1995. Reconstructive surgery was performed in 24 children (29 ears). Calf-vein xenografts were used for myringoplasty and for the lining of the bony walls of the postoperative cavity (of the created external auditory canal and of the mastoid cavity). Hearing improvement was gained in 79% of cases, and in 55% of patients it was 24 dB or higher. Patent and epithelilized external auditory canals were obtained in 81% of the operated "atretic" ears. Failures referred to fibrodermal restenosis and lack of hearing improvement. Surgical treatment of bilateral congenital aural "atresia" can be performed in children at 4-6 years of age. Vein xenografts are a good reconstructive material recommended in congenital aural malformations for myringoplasty and canaloplasty.

Adolescent↗

[A case of rarely observed cause of congenital dyspnea].

The authors describe a rare case of congenital dyspnoë caused by "pulmonary artery sling". They indicate a role of early diagnosis based on additional diagnostic investigation as bronchoscopy, bronchography and oesophagoradiography. Surgical correction of the vascular ring allows to maintain the child's life and gives possibility of normal further development.

Bronchography↗

[The use of the ox's vein for myringotomy of the ear].

The study presents a modification of the method developed by Zini et al. to prepare an ox's vein for a myringoplasty. The graft of the vein was pickled in a trypsin solution, fixed in formaldehyde and stored in a 70% ethanol solution. It was established that the incubation period of the vein in the trypsin solution required to produce the best histological specimens for this purpose was 5 hours. The preparation of the ox vein for a graft with the use of trypsin is relatively simple and inexpensive. Xenografts of ox veins for use in myringoplasties in humans are a good material and may be successfully used both in reconstructions of large defects in the tympanic membrane and in operations to correct congenital atresia of the ear.

Animals↗

Dominant symphalangism and conductive hearing loss.

Dominant symphalangism in three generations is presented in this paper. Conductive hearing loss of a 14 year old male patient with proximal symphalangism was due to fixation of the stapes.

Abnormalities, Multiple↗

[An atypical case of Wegener's granulomatosis complicated by sepsis and coxitis].

There is presented an atypical case Wegener's granulomatosis of maxillo-nasal region without bony destruction. The case is unusual because of sepsis and purulent coxitis. The patient responded well to treatment with vincristine and cyclophosphamide. ANCA assays have very good sensitivity and specificity for Wegener's granulomatosis.

Adolescent↗