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Biomedical subjects

A Mallya

Publications and source records attributed to A Mallya.

11 recordsLinked to original sources
PubMed1992

Discontinuation of a psychogeriatric program for nursing home residents: psychotropic medication changes and behavioral reactions.

Changes in medications and behavior were recorded for residents of three nursing homes where a psychogeriatric rehabilitative program was either absent, maintained, or discontinued. Residents without the program received the greatest number of psychotropics. Discontinuation of the program was associated with two problems: (a) fewer reductions in medications and (b) more behavioral difficulties among clients with medication increases. The nursing home with continuous services was the only one where all types of medication changes were followed by an overall decrease in behavior problems or no problems at all.

Aged↗
PubMed1979

Naloxone fails to affect short-term memory in man.

The effects of naloxone on memory were studied in 26 healthy male volunteers. Either placebo, or 10 mg, or 20 mg of naloxone was given iv on separate occasions. Ten minutes after each injection, the subjects listened to 8 lists of words (10 words on each list). Immediate recall, delayed recall, and delayed recognition were not affected by naloxone within 60 minutes of its administration. These results provide no support for the hypothesis that edorphins play a role in the short-term auditory memory in man.

Adult↗
PubMed1979

EEG and other effects of naltrexone and heroin in man.

This paper reviews older results on EEG and behavioral effects of heroin and opiate antagonists in exaddicts, and presents new findings on the effects of naltrexone in men who have never been addicted. Ten normal volunteers were given on three separate occasions placebo, 50 mg or 100 mg of naltrexone. The average alpha frequency was significantly slower after naltrexone than after placebo. Naltrexone elicited a significant reduction of breathing rate and oral temperature. Those results indicate that naltrexone does not act as a pure narcotic antagonist in non-addicted men.

Auditory Threshold↗
PubMed1977

Naloxone in chronic schizophrenia.

The specific narcotic antagonist naloxone (0.4 milligram) was given intravenously to seven chronic schizophrenics who reported that they had very frequent auditory hallucinations. Saline solution was used as a placebo. The coded study did not reveal any effect of naloxone on hallucinations or on global psychopathology.

Adult↗