PubMed Health⌕ Search

Biomedical subjects

A Marczyńska

Publications and source records attributed to A Marczyńska.

At least 19 recordsLinked to original sources
PubMed1990

CA-50 serum level in patients with prostate cancer.

CA-50 antigen is considered to be a generalized carcinoma-associated antigen. CA-50 serum levels were measured by solid phase radioimmunoassay using a specific monoclonal antibody. Sera of 49 patients with prostatic cancer of different clinical stages, 43 patients suffering from BPH, and 28 healthy males were tested. Positive test results were observed in 57.1% of patients with prostate cancer values ranging from 42.9% in stage A to 66.7% in stage D. Increased CA-50 levels were found in 11.6% of patients with BPH.

Aged↗
PubMed1988

Serum tissue polypeptide antigen (TPA) and prostatic acid phosphatase (PAP) in patients with prostatic cancer.

Concurrent measurements of serum TPA and PAP concentrations by double antibody radioimmunoassays were done in 49 patients with prostatic cancer in different clinical stages. The reference group comprised patients suffering from BPH. Positive TPA was found in 32.7% of cancer patients, the lowest percentage in stage A (11.1%) and the highest in stage D (55.6%). The additional value as a diagnostic aid of the TPA test was revealed on the basis of examination of the selected group of patients with not increased PAP. Positive TPA was found in 16.7% of patients: none in stage A, 22.2% in stage B, and 33.3% in stage D. Prostatic cancer remains the most common malignancy of the genitourinary tract. The improvement in the results of treatment involves not only a modernization of treatment modalities but also the introduction of laboratory tests which give the most ample information on the stage of tumour development and improve possibilities to control tumour therapy. Besides the refinement of the determination procedures of specific prostatic markers, prostatic acid phosphatase (PAP), through radio- and enzyme-immunological methods, there is a search for additional markers which might be helpful in diagnosis and follow-up of treatment.

Acid Phosphatase↗
PubMed1983

Serum proteins in patients with benign prostatic hyperplasia.

Studies of serum protein patterns done in a group of 42 patients with benign prostatic hyperplasia (PBH) revealed the following: (1) prior to the operation significant hypalbuminaemia and increase of alpha 2-, beta- and gamma-globulins, IgG, IgA, IgM and CRP levels; (2) 12 days after operation a marked decrease of albumin concentration, increase of alpha 2-globulin and a sharp rise of CRP; (3) after 1 year a decrease of hypalbuminaemia and increase of alpha 2- and beta-globulins and CRP; in contrast to that, there was further increase of gamma-globulin concentration expressed also in the IgG, IgA and IgM levels.

Aged↗
PubMed1983

The concentration of zinc in relation to fundamental elements in the diseased human prostate.

Studies of the composition of prostatic tissue revealed significant decreases not only of the zinc but also of the potassium concentration, in the cancerous tissue, whereas the nitrogen, phosphorus and magnesium concentrations were within normal limits. The composition of hyperplastic prostatic tissue was similar to the normal except for a tendency towards decreased nitrogen concentration.

Adult↗