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A Martínez Vea

Publications and source records attributed to A Martínez Vea.

At least 19 recordsLinked to original sources
PubMed2002

[Polymorphism of the renin-angiotensin system and renal failure].

The renin-angiotenin-aldosterone system (RAAS) is not only involved in cardiovascular disease but also in renal pathophysiology and progression of renal disease. Several polymorphisms of genes coding for components of the RAAS have been identified. The I/D polymorphism of the ACE gene, a variant of the angiotensiogen gen, the M235T polymorphism, and the variant A1166 C polymorphism of the angiotensin II type 1 receptor gene are the most important. Several studies have suggested a potential role for I/D polymorphism of the ACE gen in the progression of renal diseases and in the cardiovascular death rate of patients with renal failure. Data on RAAS polymorphisms as determinants of the prevalence of renal diseases and the response to renoprotective therapies are conflicting. Given the polygenic nature of renal and cardiovascular disease and the growing number of candidate genes, large prospective and collaborative studies are required to assess the effect of RAAS polymorphisms on the progression of renal disease and on the response to renoprotective therapies.

Cardiovascular Diseases↗
PubMed1981

[Oliguric and non-oliguric renal failure in high risk patient in intensive care units (author's transl)].

Oliguric and non-oliguric acute renal failure was studied in a group of 28 high risk patients in an intensive care unit. Of these, 15 (53.5%) presented oliguric and 13 (46.4%) non oliguric acute renal failure. Causal agents of the renal failure were postoperative in 14 cases, mainly peritonitis; medical in 10 and posttraumatic in 4. Oliguric renal failure was most commonly medical, while non-oliguric renal failure was predominantly postoperative in origin (p less than 0.05). Results of urinalysis indicative of renal failure were similar in both groups: NAO, osmolarity, FeNa, BUN o/p and creatinine o/p, as were degree and course of renal failure, and the appearance of complications and indications for dialysis. There was no significant difference in mortality rate between oliguric (93%) and non-oliguric (85%) patients; total mortality was 89%. The results of this study clearly show that non-oliguric acute renal failure carries the same poor prognosis in high risk patients in intensive care units as do the oliguric forms of the entity.

Acute Kidney Injury↗
PubMed1980

[Acute appendicitis in the elderly (author's transl)].

The mortality rate and clinical, analytical, radiographic and pathologic data from 31 patients with acute appendicitis over 60 years of age are compared to those from 100 patients under 60. The elderly group showed a greater delay in medical consulting, a more diffuse abdominal pain and a greater incidence of perforated and gangrenous appendicitis. This last fact could be related not only to the consulting delay, but also to the own characteristics of the aged appendix. There were no significant differences between both groups regarding analytical results and radiographic findings. Mortality rate was 13 percent in the elderly, while it was null in the younger series.

Acute Disease↗