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Biomedical subjects

A Martínez-Ramos

Publications and source records attributed to A Martínez-Ramos.

6 recordsLinked to original sources
PubMedDate not supplied

[Characterization of a substance which protects Klebsiella pneumoniae from the bactericidal effect of normal human serum].

Chemical composition of a substance produced by Klebsiella pneumoniae which is accumulated in chemically defined medium was determined. This substance (the protective factor) protects the bacterium from being killed by normal human serum. Protective factor was treated with DNase, lysozyme and an alkaline protease. The two former enzymes did not affect the protective factor. On the other hand, when alkaline protease was used, the protective activity was totally lost. Results showed that the protective factor is a protein.

Bacterial Proteins↗
PubMedDate not supplied

[Substance produced by Klebsiella pneumoniae with protects it from the bactericidal effect of normal human serum].

A Klebsiella pneumoniae culture in Fouad's chemically defined medium, which was grown from 18 to 24 hours at 37 degrees C was prepared. Bacterial cells were eliminated by centrifugation and the supernatant was sterilized by Millipore membrane filtration. A protective activity against normal human serum bactericidal effect on K. pneumoniae K-9 and K-13 was ascribed to sterile filtrate. The protective filtrate seems to be a high molecular weight substance.

Biological Factors↗
PubMedDate not supplied

[Classification of Klebsiella strains with lectins].

Fourteen different plant seeds were used to obtain lectins which in turn were used to agglutinate 72 different serological strains of Klebsiella. The results were used to design a scheme which distinguishes 62 serotypes (91.6%) with a unique agglutination pattern with lectins. Two pairs of strains as well as two sets of three strains gave the same patterns. This procedure is useful as an alternative in the identification of strains for epidemiological purposes.

Agglutination Tests↗
PubMedDate not supplied

[Capsular polysaccharide of Klebsiella pneumoniae. II. Immunogenic properties].

It has been considered that the polysaccharide capsular material from microorganisms such as Klebsiella pneumoniae induces mainly thymus-independent humoral immunity, nevertheless studies done with Bacteroides fragilis have shown the participation of cellular immune effector mechanisms. Works done to define the immunogenic role of the capsular polysaccharide of Klebsiella pneumoniae indicate that both active and passive immunization with these antigens confer protection against infections with this bacteria. Several studies propose the use of vaccines prepared with one or various capsular serotypes of Klebsiella pneumoniae in immunoprophylaxis or immunotherapy.

Animals↗