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A Marton

Publications and source records attributed to A Marton.

50 records · Page 3Linked to original sources
PubMed1987

The effect of EDTA-Fe(III) complexes with different chemical structure on the lipid peroxidation in brain microsomes.

Unlike EDTA-Fe(III) (1:1), the oxidized form of EDTA-Fe(II) complex enhanced lipid peroxidation in brain microsomes. Mossbauer spectroscopy and electron paramagnetic resonance analysis of oxidized EDTA-Fe(II), capable of inducing lipid peroxidation, showed the presence of EDTA-Fe(III) complex, which was different from the separately prepared (not oxidized) EDTA-Fe(III). Lipid peroxidation initiated by the oxidized EDTA-Fe(II) complex was dependent on the presence of NAD(P)H and functionally intact microsomes. No inhibitory effect was found by generally used free radical scavengers and catalase. Our results clearly indicate that the chemically different EDTA-Fe(III) complexes differ in their capability of initiating the NAD(P)H-dependent lipid peroxidation in brain microsomes.

Animals↗
PubMed1986

Synthetic estimates for small areas: problems and results of a simulation experiment.

The use of special estimation techniques to develop small area data is described using examples from Hungary. The focus is on the use of synthetic, or SPREE, techniques to increase the reliability of estimates of small-area characteristics. The techniques are tested using a simulation experiment. "Ten variables were selected from the 1980 population census. Their exact values were known. Four different synthetic estimators were tested and compared with the simple direct estimator. The ten variables were studied at both a fairly aggregated level (minor domains) and in great detail (mini domains). The simple direct estimator with the synthetic or composite synthetic estimators shows an improvement of average reliability of 40 to 50 per cent."

Developed Countries↗
PubMed1986

Effect of a heme-peptide derived from cytochrome-c on lipid peroxidation. I. Effects on brain microsomes.

Heme-nonapeptide inhibits NADH and NADPH dependent lipid peroxidation of brain microsomes in the presence or absence of ADP-Fe complex. The transient accumulation of lipid peroxides during NADH or NADPH dependent, ADP-Fe stimulated lipid peroxidation, is inhibited by heme-nonapeptide. Oxygen consumption of brain microsomes in the presence of NADH or NADPH is stimulated by heme-nonapeptide. Reduction of cytochrome-c and nitro-tetrazolium-blue by O2- generated by xanthine oxidase is inhibited by heme-nonapeptide.

Adenosine Diphosphate↗
PubMed1986

Serological studies in Chlamydia trachomatis associated pneumonia of infants.

Serological results provided evidence for the clinical diagnosis of chlamydial pneumonia in 8 out of 51 cases. Elevated chlamydia-specific IgM titres (128-2048) and IgG titres (128-2048) were recorded in 5 and 8 infants, respectively. High titres of chlamydial antibodies (512-8192) in the sera of mothers of seropositive children proved genital Chlamydia trachomatis infection.

Antibodies, Bacterial↗
PubMed1985

Inhibition of lipid peroxidation by heme-nonapeptide derived from cytochrome c.

Heme-nonapeptide, derived from cytochrome c, inhibited both the NADPH- and NADH-dependent lipid peroxidation of brain microsomes but, in the case of liver microsomes, this inhibitory effect manifested itself in the presence of SKF-525A (a specific blocker of cytochrome P-450) only. Heme-nonapeptide prevented the transient accumulation of lipid peroxides in microsomes during lipid peroxidation. The oxygen consumption of microsomes in the presence of NADPH or NADH was stimulated by heme-nonapeptide. From these results we concluded that, in vitro, there are two independent mechanisms of lipid peroxidation in liver microsomes. It is suggested that, in vivo, the heme-peptide-sensitive mechanism, observed in brain microsomes, is more important.

Animals↗
PubMed1984

Virulence factors of Escherichia coli. I. Mannose resistant haemagglutinating capacity is associated with serogroup but not with site of infection.

Different serogroups of Escherichia coli strains originating from faeces (patients with enteritis 244, healthy individuals 225), urine (pyelonephritis 111, cystitis 130, asymptomatic bacteriuria 59) and other extraintestinal sources (blood 30, cerebrospinal fluid 15, wound 13, autopsy material 9, umbilicus 8, vagina 20, throat 13 and nose swabs 5) were examined for mannose resistant haemagglutination of human A erythrocytes (MRHA hum.). The most frequent serogroups were O1, O2, O4, O6, O7, O18 and O75 uniformly among faecal (26.5%), urinary (34%) and other extraintestinal (57.9%) strains. Haemagglutinating activity was significantly more frequent in these serogroups than in others (p less than 0.001). There was no significant association between MRHA positivity and origin of the serogroups. It has been concluded that MRHA hum. property of an E. coli strain depends on its serogroup rather than its origin. As these serogroups are the most frequent in the intestinal flora, it is assumed that their physiological function is to colonize the bowel and their pathological significance is to provide a source for extraintestinal infection.

ABO Blood-Group System↗
PubMed1984

Diagnostic experience in two cases of legionellosis.

Sera of 30 patients with atypical pneumonia were tested for antibodies against the representative strains of Legionella pneumophila 1-6 serogroups and 4 species of legionella-like organisms. Investigations were carried out with indirect immunofluorescence assay. The sera of 2 patients gave a titre of 2048 and 1024 with serogroup 5 and 4, respectively. The high antilegionella IgM titres were indicative of recent infections. Legionellae were not detected in transtracheal aspirate and in autopsy material.

Adult↗
PubMed1982

Sensitizing activity to egg protein of an A1PO4-adjuvant full-virus influenza vaccine.

The sensitizing activity to egg protein of an A1PO4-adjuvant purified and concentrated influenza-A vaccine was examined in animal experiments and in man. Intravenous injection of ovalbumin caused anaphylactic symptoms and/or fatal anaphylactic shock in prevaccinated guinea-pigs. Ovalbumin-specific antibodies detectable by the passive haemagglutination reaction (PHA) appeared in the blood serum of the vaccinated animals. Model experiments with purified ovalbumin suggested that 1 human dose of the vaccine contained egg protein in the range from 0.1 to 1 ng, and that the antigenic effect of the vaccine grew to more than 10(3)-fold by its adsorption to A1PO4 gel. Adults who in previous years had been immunized with similarly prepared influenza vaccine several times responded with mild reactions; symptoms suggestive of hyperergy did not occur, irrespective of the vaccination history. In the prevaccination serum sample of some vaccines, ovalbumin-specific PHA antibodies were found up to titres independent of the number of the previous immunizations. The concentration of the ovalbumin-specific antibodies of the IgE class was by several orders of magnitude lower in the postvaccination samples than in the serum of some patients hypersensitive to egg protein.

Adjuvants, Immunologic↗
PubMedDate not supplied

[Tracheal injury].

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Adult↗