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Biomedical subjects

A Mayo Iscar

Publications and source records attributed to A Mayo Iscar.

6 recordsLinked to original sources
PubMed2004

[Experimental study on usefulness of silicone-fluorsilicone copolymer oil (SiFO) in vitreoretinal surgery].

PURPOSE: To evaluate the usefulness of silicone-fluorsilicone copolymer oil (SiFO) as an intraoperative tool and a vitreous substitute in vitreoretinal surgery. METHODS: Handling properties of SiFO were tested and compared with those of perfluorooctane (PFO). The transparency of both substances was measured by spectrophotometry and subjectively assessed. Their tendency to dispersion was observed during injection in balanced saline solution (BSS) and after mechanized and manual shaking. Ease of injection and aspiration through small-gauge instruments was evaluated. Ocular tolerance to SiFO and PFO was studied after intravitreal injection in rabbit eyes: intraocular pressure, anterior segment inflammatory response and dispersion were evaluated, and a histopathological study was performed. RESULTS: Injection and aspiration of SiFO were more difficult than those of PFO because of its higher viscosity. PFO dispersed progressively into small droplets as early as two days after intravitreal injection, whereas SiFO remained as a single bubble for 14 days. Histopathologically both substances induced an inflammatory response over the inferior retina, with microvacuolated macrophages and foreign body giant cells, which were larger in eyes wearing SiFO. CONCLUSIONS: SiFO may be useful as an intraoperative tool, although its main drawback is a more difficult injection and aspiration compared to PFO. It has been well tolerated as a short-term vitreous substitute, but further clinical studies are needed.

Animals↗
PubMed2003

[Dry eye signs and symptoms in hydrogel contact lens wearers: relation to smoking habit].

PURPOSE: To determine whether there may be a relationship between the smoking habit ant the presence of dry eye signs and symptoms in a population of hydrogel contact lens (HCL) wearers. MATERIAL AND METHODS: 60 adults HCL wearers were chosen randomly. The sample was divided into three groups: nonsmokers, smokers of less than 15 cigarettes per day and smokers of more than 15 cigarettes per day. The ocular symptoms were evaluated with a questionnaire (modified Mc Monnies test). Evaluation of tear meniscus, Schirmer test with anesthesia, non invasive break-up time (NIBUT), slit lamp examination and fluorescein staining were performed to assess ocular signs of dry eye. RESULTS: No significant differences were found among the three study groups. CONCLUSION: Smoking does not seem to affect the presence of signs and symptoms of ocular dryness in a population of HCL wearers and does not predispose to contact lens intolerance.

Adult↗
PubMed2002

[Use of systemic antibiotics in Valladolid (1996-2000)].

A longitudinal retrospective study was conducted to analyze the changes in the use of systemic antibiotics from 1996 to 2000 in the province of Valladolid, Spain. The use of systemic antibiotics was determined according to the defined daily dose and showed a progressive increase during the first four years of the study, followed by a large decrease in the year 2000. When examined by subgroup, wide spectrum penicillins accounted for almost 60% of the antibiotics consumed, and were therefore responsible for this change. Macrolides represented 16.4% of the consumption, which increased during the whole study period. Quinolones, with 9.3% of the total, showed a slow but steady increase. Cephalosporins accounted for 8.1%, with their use decreasing since 1998. It was concluded that wide spectrum penicillins were the most used systemic antibiotics in the study population, although a decreasing trend in their use and an increase in the use of macrolides and quinolones was observed.

Anti-Bacterial Agents↗