[The influence of environmental changes on the central nervous system].
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Biomedical subjects
Publications and source records attributed to A Mello.
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In the present paper a formula appropiate to stroke volume estimation in the experimental animal is presented. Based in the indicator concentration difference during the two diastoles which follows the indicator injection on the ventricle chamber, the electric conductivity through impedance recording indicates these concentration. Appropiate procedures and a calibrating scale are used in order to obtain these two concentrations. From the stroke volume which appears as changes in impedance measured between a pair of electrodes located at the apex and base of the ventricle and the data obtained through the formula, the cardiac output and ventricular volume can be calculated.
The cardiac output evaluation is usually realized through indicator dilution techniques and this principle was applied to ventricular volume measurements. However this approach has been criticized by several workers. Based on the recently developed association of indicator dilution method with intraventricular impedance recording to cardiac output determinations, the present investigation was designed to analize the dipersion pattern of saline solution within the ventricle. Three bipolar eletrodes were placed in different positions on the left ventricle in order to record the duration in seconds, for the saline to reach these positions. The detection of the saline was done through conductibility changes at the eletrodes ends. The results indicate a time duration smaller to the indicator dispersion than those of the diastole duration, simultaneously measured.