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Biomedical subjects

A Mert

Publications and source records attributed to A Mert.

At least 55 records · Page 3Linked to original sources
PubMed1998

Bronchobiliary fistula due to alveolar hydatid disease: report of three cases.

Bronchobiliary fistula is a serious complication of echinococcosis of the liver. Surgical and endoscopic treatments have been used successfully in the management of bronchobiliary fistula due to hepatic hydatid cysts. However, very little information exists on the management of bronchobiliary fistula due to alveolar hydatid disease. We report here the efficacy of various potential therapies in three cases.

Adult↗
PubMed1997

Long-term efficacy of interferon-alpha and ursodeoxycholic acid in treatment of chronic type C hepatitis.

Interferon-alpha (IFN) and ursodeoxycholic acid (UDCA) combined have a controversial role in the treatment of chronic type C hepatitis. We studied the long-term efficacy of both drugs alone or in combination. In a three-year period, 108 patients were randomized into three treatment arms: (1) IFN alone 3 MU three times a week (N = 49), (2) IFN 3 MU three times a week + UDCA 250 mg twice a day (N = 45), and (3) UDCA alone 250 mg twice a day (N = 14). Response was defined as complete normalization of serum ALT. For the responders at the end of six months, the treatment was run to 12 months. Nonresponders (NRs) of the first group were crossed over to combination and NRs of the combination received 6 MU three times a week IFN+UDCA for the next six months. The enrollment to the UDCA alone arm was stopped early, since only 1/14 normalized serum ALT at the end of third month. However, 12/14 completed six months and 11 NRs received IFN 3 MU three times a week alone for the next six months. Twelve discontinued treatment due to side effects. Responders were followed-up untreated for 18 months. Sustained response (SR) was defined as persistence of normal serum ALT levels in this period. At the end of six months, 22/45 (48%) from the IFN-alone and 23/39 (58%) from the combination group responded. Twenty NRs from former and 15 of latter group were crossed over. While none of the 20 from the IFN-alone group responded to the combination, 1/15 NRs of the combination group responded to dose escalation. SR was achieved in 9/45 (20%) of the IFN alone and 7/39 (18%) of the combination group. The mean time form the end of the treatment to the relapse was not different between the groups. Five of 11 UDCA NRs responded to IFN with SR in 2. It was concluded that UDCA as a single agent is ineffective in achieving response in the treatment of chronic type C hepatitis. Combined with IFN, it increases response rate insignificantly although this is not sustained.

Alanine Transaminase↗
PubMed1993

[Isolation of Gardnerella vaginalis from vaginal discharge specimens].

In this study specimens taken from 93 patients who admitted to outpatient clinics of SSK Ankara Gynaecology and Obstetrics Hospital with vaginal discharge were examined for G. vaginalis, T. vaginalis, C. albicans and N. gonorrhoeae. We evaluated the smell, pH, direct microscopic examinations, stained preparations and specific culture results of the discharges which were taken from posterior fornix. We isolated G. vaginalis from 13 patients (13.9%), T. vaginalis from 5 patients (5.3%) and C. albicans from 19 patients (20.4%). N. gonorrhoeae could not be isolated from any of the specimens. In our control study, we isolated G. vaginalis in three out of 50 patients (6%) without vaginal discharge. We observed T. vaginalis in specimens of 3 control patients. C. albicans and N. gonorrhoeae could not be isolated in this study in this study.

Adult↗
PubMed1992

[Prevalence of hepatitis C virus antibodies in hospital personnel].

In this study, 416 hospital staffs from different departments and profession were screened for Hepatitis C virus (HCV) antibody by Enzyme Immune Assay method. Two hundred fifty blood bank donors were tested as a control group. Anti HCV positivity were found in four of hospital staffs (0.9%) and in four of donors (1.6%). According to our results, generally we didn't find any data about transmission of hepatitis C virus from hospital but it is interesting that all of the positive cases were from intensive care units.

Blood Donors↗
PubMed1991

[Penicillin resistance in gonococcal urethritis].

In this study, we researched the resistance of gonococci to penicillin among 30 patients who had urethral discharge because of gonococcal urethritis, between 1990 January and 1990 September at SSK Ankara Hospital. We established 26.6% of isolated 30 Neisseria gonorrhoeae species resistant to penicillin.

Adult↗
PubMed1988

[Shigella serotypes and drug resistance patterns of strains isolated in Etimesgut, Turkey, in 1987].

Drug resistance patterns of shigella strains were investigated in a prospective manner in Etimesgut district during a period of 1 year. Thirty strains shigella were isolated, belonged to three subgroups with preponderance of Sh. flexneri (70%), followed by Sh. sonnei (27%) and Sh. boydii (3%). The resistance was highest with streptomycin (80%), followed by trimethoprim-sulfamethoxazole (TMP-SMZ) (53%) and ampicillin (43%). Only three strains (10%) were sensitive to all eight antibiotics tested. Sixteen (53%) were resistant to three or more antibiotics. The data showed an increase in resistance to the commonly used antimicrobial agents--namely IMP-SMZ and ampicillin. IMP-SMZ is no longer the drug of choice in severe shigellosis, at least in this region of Turkey.

Ampicillin Resistance↗
PubMed1984

[A case of diphtheria resulting in death].

A 10 years old girl admitted to the hospital on 7.5.1983. She was sent from Etimesgut Hospital with the preliminary diagnosis of diphtheria bronchopneumonia, and glomerulonephritis. Cultures taken from the throat and nose of the patient yielded toxigenic diphtheria bacilli. Inspite of antitoxin and antibiotic treatment and a tracheostomy the patient died two days later. Diphtheritic membranes occluding larynx and trachea were found at the autopsy. In six out of the nine of the family members the throat cultures were found to be positive for toxigenic C. diphtheriae. The family was visited by a woman who had a bloody nasal discharge and ulcers around her nostrils. Close contacts, including the neighbours and the classmates of the children were checked for diphtheria bacilli and all were found to be negative.

Bronchopneumonia↗
PubMedDate not supplied

Abdominal actinomycosis: a report of two cases.

Actinomyces spp. cause a chronic suppurative, granulomatous disease which is characterized clinically by extensive abscess formation, recurrent draining of sinuses and fistulae and histologically by the presence of the so-called "sulphur granules". Colonic actinomycosis is a relatively rare infection and its diagnosis is difficult. We report the case of a female patient who was operated on for ovarian cyst and the case of another female patient operated on for a mass in the transverse colon. In both cases the pathology of the excised tissues revealed actinomycosis. Actinomycosis must be considered in the differential diagnosis of patients who present with abdominal pain, fever, leucocytosis and intestinal wall thickness and/or abdominal mass.

Abdomen↗