American Society of Maxillofacial Surgeons, 1997 to 2006: another decade of excellence in education and research.
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History, 20th Century↗
Biomedical subjects
A Michael Sadove
Publications and source records attributed to A Michael Sadove.
Treatment of nasopharyngeal stenosis by prosthetic hollow stents: Clinical experience in eight patients.
OBJECTIVE: A series of nasopharyngeal appliance designs is presented that represents our evolving experience over a 20-year period in the adjunctive use of prosthetic stents in the surgical correction of nasopharyngeal stenosis. DESIGN: Retrospective assessment of effectiveness of two nasopharyngeal stenosis hollow stent designs in a consecutive series of patients for relief of nasal obstructive symptoms. SETTING: Tertiary academic medical center, Craniofacial Program at Children's Hospital. PATIENTS: Four patients with nasopharyngeal stenosis were treated with a preoperatively fabricated stent made from a clasped palatal appliance onto which hollow acrylic conduits were extended through surgically re-created pharyngeal ports. A subsequent set of four patients with nasopharyngeal stenosis were treated with intraoperatively-fashioned silastic grommets, as opposed to palatal appliances. INTERVENTIONS: Postoperative intraoral stenting of nasopharyngeal ports. MAIN OUTCOME MEASURES: Maintenance of pharyngeal port opening after 1 year, improvement in nasal airway obstructive symptoms. RESULTS: The palatal appliance stents were less well tolerated and had a lower maintenance of port patency after device removal (4 of 8, 50%). The silastic grommets provided better retention into the ports and increased patient tolerance, as well as better 1-year port maintenance (6 of 8, 75%). CONCLUSIONS: The grommet stent appliance offers numerous advantages over a conventional dental-clasped appliance for prosthetic nasopharyngeal stenting, including obviation of extensive preoperative preparation, ease of insertion and removal, and exchange of air during the stenting period. Improved nasopharyngeal patency with this device may be due to greater patient tolerance and subsequent longer use.
Adolescent↗
Treatment of pediatric breast problems.
Pediatric breast anomalies are relatively common. Treatment options depend on whether the abnormalities are hyperplastic, deformational, or hypoplastic. Hyperplastic anomalies require reduction techniques, whereas deformational and hypoplastic lesions require augmentation techniques and are more likely to require revisional surgeries. These designations aid the surgeon in decision-making about timing for treatment and in optimizing aesthetic outcomes.
Adolescent↗
Congenital and acquired pediatric breast anomalies: a review of 20 years' experience.
BACKGROUND: The purpose of this article was to review the senior author's 20 years of experience in the treatment of pediatric breast abnormalities, to propose a classification system for their treatment, and to provide a synopsis of treatment options. METHODS: Congenital and acquired breast anomalies were identified in a retrospective chart review (n = 66). Breast abnormalities were classified as hyperplastic (n = 44), deformational (n = 11), or hypoplastic (n = 11). Hyperplastic abnormalities included gynecomastia, hyperplasia, polythelia, polymastia, and giant fibroadenoma. Deformational abnormalities were categorized as either iatrogenic (previous thoracostomy, thoracotomy, or tumor excision) or traumatic (thermal or penetrating injuries). Hypoplastic abnormalities included athelia, unilateral and bilateral hypoplasia, tuberous breast, and Poland syndrome. Type of surgery, age at initial operation, and number of operations were recorded for all patients. RESULTS: Hyperplastic abnormalities were treated with breast reduction techniques and required the fewest operations per patient (1.14), followed by iatrogenic breast injury (2.1 per patient). The average number of procedures required for hypoplastic abnormalities was 2.45 per patient. The highest reoperation rates were seen in patients with burn injuries to the breast and patients with Poland syndrome. Mean age at initial operation was highest in the deformational group (18.5 years) and lowest in the hyperplastic group (17.4 years). CONCLUSION: Classification of pediatric breast abnormalities and considerations about timing for surgery and the likely need for staged operations aid in anticipating and optimizing clinical outcomes.
Adolescent↗
The spectrum of orofacial clefting.
LEARNING OBJECTIVES: After studying this article, the participant should be able to: 1. Describe the differing types of congenital clefting defects that extend outward from the perioral region. 2. Define the sites of anatomical disruption and deformities that these types of facial clefts cause. 3. Describe the cause and incidence, if known, of orofacial clefts and their inheritance/transmission risks. BACKGROUND: Clefts of the orofacial region are among the most common congenital facial defects. The clinical presentation is usually that of a lateral cleft of the lip through the philtrum with or without extension through the palatal shelves. However, atypical forms of clefts with lip involvement also occur in a variety of patterns, some of which are embryologically predictable; others are not. METHODS: An overview of the embryology, cause, and incidence of this diverse and interesting group of congenital orofacial clefts is presented. RESULTS: Clefts involving the lateral upper lip; median upper lip; and oblique facial, lateral facial, and median mandibular regions are reviewed. CONCLUSIONS: This review of orofacial malformations describes clefting anomalies that emanate from the mouth and lips. As the causes of orofacial clefts are better understood, it is becoming clear that a complex interplay between genetic and environmental variables causes these clefts. Future study of orofacial clefts will require increasingly sophisticated methods of elucidating these subtle interactions.
Abnormalities, Multiple↗
Surgical technique for primary alveolar bone grafting.
Bone grafting of the alveolar cleft is an important component of the comprehensive care of the cleft lip and palate patient. Although debate exists regarding the optimal timing of the procedure, one approach is the placement of a rib graft in the alveolar cleft before eruption of the deciduous canine (primary alveolar bone graft). Since 1982, primary alveolar bone grafting has been performed at our institution in more than 300 patients. Because little is reported in the literature on primary alveolar bone grafting in general, an experienced surgical technique and protocol are lacking. Our surgical technique for rib graft harvest as well as alveolar bone graft placement in the infant cleft alveolus is described.
Alveolar Process↗
Congenital nevus: the Indiana University's approach to treatment.
The article will review the different treatment modalities for congenital nevi and the senior author's approach to these lesions. The management of congenital melanocytic nevus presents a diagnostic dilemma. Treatment must weigh the risk of malignancy, psychological distress to parents and child, and potential morbidities of excision. Excision of every nevus is neither applicable nor practical. Most plastic surgeons would agree that a large nevus mandates excision because of the risk of malignancy. However, debates occur regarding treatment of small and medium size nevi. Opinions differ regarding the types of reconstruction, malignant potential, and psychological impact of leaving a lesion untreated.
Cell Transformation, Neoplastic↗
Resorbable PLLA-PGA plate and screw fixation in pediatric craniofacial surgery: clinical experience in 1883 patients.
The need to provide rigid bony fixation in the surgical treatment of craniofacial deformities has inspired an on-going evolution of surgical innovations and implants. Because of the young age of many treated craniosynostosis patients and the unique pattern of cranial vault growth, the extensive implantation of metal devices is potentially problematic. The use of resorbable plate and screw devices offers all of the benefits of rigid fixation without many of their potential risks. Since the introduction of resorbable plate and screw devices in 1996, tens of thousands of craniofacial patients have received implants, but long-term results from a large series have yet to be reported. A combined prospective and retrospective analysis was done on 1883 craniosynostosis patients under 2 years of age treated by 12 surgeons from seven different geographic locations over a 5-year period who used the same type of resorbable bone fixation devices (poly-L-lacticpolyglycolic copolymer). Specifically, the incidence of postoperative infection, fixation device failure, occurrence of delayed foreign-body reactions, and the need for reoperation resulting from device-related problems were determined. Technical difficulties and trends in device use were also noted. From this series, significant infectious complications occurred in 0.2 percent, device instability primarily resulting from postoperative trauma occurred in 0.3 percent, and self-limiting local foreign-body reactions occurred in 0.7 percent of the treated patients. The overall reoperation rate attributable to identifiable device-related problems was 0.3 percent. Improved bony stability was gained by using the longest plate geometries/configurations possible and bone grafting any significant gaps across plated areas that were structurally important. The specific types of plates and screws used evolved over the study period from simple plates, meshes, and threaded screws to application-specific plates and threadless push screws whose use varied among the involved surgeons. This report documents the safety and long-term value of the use of resorbable (LactoSorb) plate and screw fixation in pediatric craniofacial surgery in the infant and young child. Device-related complications requiring reoperation occurred in less than 0.5 percent of the implanted patients, which is less frequent than is reported for metallic bone fixation. Resorbable bone fixation for the rapidly growing cranial vault has fewer potential complications than the traditional use of metal plates, screws, and wires.
Absorbable Implants↗
Cleft palate repair: art and issues.
Caring for the child with cleft palate requires a multidisciplinary approach that begins with evaluation for other possible congenital anomalies, decisions about timing of repair, and choice of techniques. Postoperative follow-up similarly requires a team approach and should include an otolaryngologist, an orthodontist, and a speech therapist. The art of cleft palate repair has enjoyed a decade rich in new developments. New techniques have been developed, and standard techniques have been refined. Most importantly, the need for prospective, randomized trials to objectively compare surgical techniques has been recognized. Initiation and completion of these trials will improve outcomes for patients with cleft palate repairs.
Child, Preschool↗
Introduction of a novel internal spring-driven craniofacial bone distraction device.
A study of craniofacial bone distraction using an internal self-expanding bone device designed by the authors was performed in a young rabbit skull model. Ten 30-day-old New Zealand white rabbits were divided into two groups: 5 underwent distraction with the device, and 5 served as controls. Serial cephalograms, defleshed skull measurements, and histological examinations were performed on the study animals. The distracted group demonstrated a significant midface lengthening and overbite compared with the control group. Histologically, more fibroblasts and osteoblasts were seen in the front nasal bone in the distracted group in comparison with the nondistracted controls. The self-expanding internal bone distractor can effectively lengthen certain facial bones in an animal model and avoid some of the disadvantages associated with the external distraction techniques. This new device offers clinical potential as a useful distraction technique, but further work is needed to determine the effects of continuous postoperative tension loads on bone healing, the amount of tension generated by certain spring loads and lengths, and the feasibility of applying this concept in confined bone spaces.
Animals↗
Large osteomas of the cranial vault.
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Adult↗
Pediatric vascular lesions.
The seminal work of Mulliken and Glowacki in 1982 elucidated the histological differences between hemangiomas and vascular malformations: the former are characterized by endothelial cell proliferation, whereas the latter contain mature endothelial cells. Hemangiomas proliferate and then involute, whereas malformations remain stable in size, growing proportionally with the child. Vascular malformations are classified by the predominant vessel type within the lesion (capillary, venous, arterial, and lymphatic). Histological classification therefore correlates with clinical behavior. Treatment of hemangiomas is generally conservative; however, intervention may be required as a result of cosmetically concerning, function-threatening (e.g., interference with eyesight), or life-threatening (e.g., airway obstruction) lesions. Options include steroid therapy, laser treatment, and/or surgical excision. Vascular malformations do not involute and are more likely to require treatment. Treatment options include embolization and surgical resection. Understanding the clinical course of pediatric vascular lesions allows the surgeon to find an appropriate balance between watchful observation, providing reassurance when appropriate, and intervention when needed.
Arteriovenous Malformations↗
Reconstruction after total penile amputation and emasculation.
Amputation of the penis and testes is a rare injury in the pediatric population. The authors describe a case of traumatic amputation of the penis and testes presenting late for surgical reconstruction. The surgical reconstruction of this phallus involved advancement of the residual erectile tissue by division of the suspensory ligaments of the penis to lengthen the phallus. A glans penis was fashioned using a full-thickness skin graft with shaft skin provided by a split-thickness skin graft. The use of a tissue expander allowed the creation of a scrotum that accepted two testicular prostheses. Reconstruction of the phallus using these techniques allowed the creation of an erectile, esthetically acceptable phallus. In the situation in which residual erectile tissue remains, this technique can be effectively used in place of musculocutaneous transfer flaps or gender reassignment.
Amputation, Traumatic↗