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Biomedical subjects

A Milone

Publications and source records attributed to A Milone.

31 records · Page 2Linked to original sources
PubMed1990

[Possible role of altered levels of plasma docosahexaenoic acid in the pathogenesis of retinitis pigmentosa. Preliminary results].

Plasma samples obtained from Retinitis Pigmentosa (R.P.) patients and controls were assayed for docosahexaenoic acid (DXA), the major fatty acid in photoreceptor cells, in order to evaluate the possibility that abnormalities in PUFA metabolism could be involved in R.P. pathogenesis. Our preliminary results show levels of plasma DXA in dominantly inherited R.P. lower than in the recessive forms and controls.

Docosahexaenoic Acids↗
PubMed1986

Effect of matrix modification by strong mineral acids on the positive fast atom bombardment mass spectra of peptides.

We report an investigation of the effect of the addition of strong mineral acids to the most commonly used matrices for fast atom bombardment mass spectrometry of peptides. Among the acids tested we found that perchloric acid has a beneficial effect on: the sensitivity, the stability of quasi-molecular ion signals. Furthermore, in the presence of basic residues, ions related to perchlorate adducts are present. These further signals may be useful in differentiating peptides containing lysine from those containing the isobaric glutamine.

Acids↗
PubMedDate not supplied

Study of the onset of autism through home movies.

The authors describe the natural history and the beginning of pervasive developmental disorders (PDD) by the observation of home movies. The sample is composed of 26 children aged 18 months to 5 or 6 years at the first consultation. The methodology used in the observation of home movies includes: (1) application of the ERC-A-III scale for recognizing the precocious symptoms of autism; (2) analysis of the coming out and coming off of social, emotional and cognitive competences. The authors, starting from the analysis of these data, describe three kinds of onset and courses of PDD: progressive, regressive and fluctuating. The authors present some conclusive considerations on the different age of PDD onset in home movies, in anamnestic reconstruction and in recall for diagnosis.

Autistic Disorder↗
PubMedDate not supplied

Early behavioral development in autistic children: the first 2 years of life through home movies.

OBJECTIVE: The main aim of the research is to study the early behavioral development in autistic children through home movies. METHODS: fifteen home movies, regarding the first 2 years of life of autistic children are compared with the home movies of 15 normal children. The films of the two groups were mixed and rated by blind ratings with the Grid for the Assessment of Normal Behavior in Infants and Toddlers. The grid is composed of 17 items grouped into three developmental areas: social competence, intersubjectivity and symbolic activity. For every area, we have identified specific children's behaviors. RESULTS: Significant differences between the two groups are found both in the range of age 0-6 for intersubjectivity, and in the ranges of age 6-12 and 18-24 for symbolic activity. CONCLUSIONS: The authors pose some hypotheses about an early-appearing impairment of intersubjectivity, the ability to represent other's state of mind, in subjects with autistic disorder.

Age Factors↗
PubMedDate not supplied

[One-day surgery: results of 3,000 surgical procedures].

AIMS: To evaluate the advantages and limits of one day surgery operations performed between January 1990 and December 2000. METHODS: Pre-operative study of out patients with indications to surgical treatment with short-stay hospitalisation and research of criteria of feasibility of day-surgical program: a) morning hospitalisation; b) surgical intervention; c) post-operative control; d) night control; e) careful evaluation of admission 24 hour after operation and instruction for house-therapy; f) program of follow-up (7 and 14 days after operation). RESULTS: Mortality 0%; immediate post-operative complications 1.8%; post-operative sequelae (one year after surgery): 0.5%; high satisfaction gradient of patients one year after treatment: 89%. DISCUSSION: The Day-Surgery seems to be, after ten years of experience, available in high number of patients, with progressive extension of indications to ever more surgical fields and results very satisfactory, in term of cost-effectiveness too, with an high compliance of the patients to surgical program.

Adolescent↗
PubMedDate not supplied

[Iatrogenic lesions of the femoral vessels during hernia surgery].

The vascular lesions in hernia surgery are difficult to be found: on the basis of three cases personally treated and on literature data, the authors dwell upon the factors that influence the frequency of this event, they discuss about the therapeutic choices and they illustrate the short and long term prognosis.

Adult↗