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Biomedical subjects

A Minonishi

Publications and source records attributed to A Minonishi.

4 recordsLinked to original sources

Fibronectin on prosthetic denture fabrication.

It is well known that fibronectin adheres to various oral bacteria and shows affinity to various components. Thus the existence fibronectin which is present in the salivary flow, acquired pellicle and dental plaque, was investigated in used acrylic resin dentures with a direct immunohistochemical fluorescent technique using antihuman fibronectin goat serum which was labeled with fluorescein isothiocyanate (FITC). It was found that fibronectin frequently was present on the surface of acrylic resin dentures.

Acrylic Resins↗

[Marginal periodontitis and the immune system. III. Differences in peripheral blood lymphocyte subsets before and after treatment in adult periodontitis patients].

The lymphocyte subsets in the peripheral blood of 8 individuals, aged 25 to 57 yr, with moderate to advanced adult periodontitis were analyzed before and after treatment by means of flow cytometry, and then compared with the findings in 20 normal adults (aged 30 to 45 yr). The results were as follows: the percentage of OKT-8+ (CD 8) in the patients (20.25 +/- 7.15%) was lower than that in normal individuals (31.50 +/- 6.03%, P less than 0.01) while the OKT-4/OKT-8 ratio (2.34 +/- 1.18) was higher than the corresponding ratio in the controls (1.23 +/- 0.37); however, there was no significant difference in the percentages of OKT-3+ (CD 3), OKT-4+ (CD 4) and Leu-12+ (CD 19) between patients and normal subjects. The percentages of OKT-3+, OKT-4+, OKT-8+, Leu-12+ and OKT-4/OKT-8 after the periodontal therapy did not show a significant difference compared with the data obtained before treatment. These results indicate that the decrease in suppressor/cytotoxic T-cell population may be a kind of pathological disposition of the initiation and/or course of adult periodontitis.

Adult↗