[Serum immunoelectrophoretic pattern in subjects exposed to atmospheric pollutants emitted by plants manufacturing artificial fertilizers].
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Biomedical subjects
Publications and source records attributed to A Misiewicz.
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For purpose of investigating porphyrine balance in people exposed to contaminants emitted by nitric plant, porphobilinogen and coproporphyrin excretion with urine was determined. Methemoglobin level in blood was a basis for evaluating exposure to contaminants. The results obtained were compared with the results of investigations done in an adequately selected control group. In people exposed to contaminants emitted by nitric plant increased methemoglobin level and increased excretion of coproporphyrins with urine were found. No significant differences in porphobilinogen excretion were observed.
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The examinations of methemoglobin and properdine levels as well as of the function of peripheral blood leukocytes in the tetranitrozolic blue reduction test (NBT) were performed in the exposed persons. The obtained results were compared with those of the control group, using statistical methods. It has been found that in persons exposed to the emitted contaminants occurs the increase of methemoglobin level, the decrease of peoperdine level and a disturbed phagocytes function. The recorded changes in the factors of nonspecific immunology, i.e. of properdine and phagocytes, can favour the development of inflammatory processes and of nonspecific diseases of the respiratory system.
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