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Biomedical subjects

A Mitsudome

Publications and source records attributed to A Mitsudome.

At least 55 records · Page 3Linked to original sources
PubMed1992

Hydrocephalus due to acute aqueductal stenosis following mumps infection: report of a case and review of the literature.

An acquired form of hydrocephalus due to aqueductal stenosis developing as a sequela of mumps virus infection of the central nervous system is presented. Percutaneous third ventriculostomy and interventriculostomy (aqueduct cannulation) were performed using a flexible fiberoptic ventriculoscope. The aqueduct was blocked with amorphous material but was cleared with the scope. This is the first case of a fulminant phase of mumps ventriculitis leading to aqueductal stenosis, which has been treated using a ventriculoscope for the first time.

Acute Disease↗
PubMed1992

[A case of subacute sclerosing panencephalitis developing 8 years after immunosuppressive treatment for acute lymphocytic leukemia].

A 13-year-old girl developed subacute sclerosing panencephalitis (SSPE) with atypical absence attacks as an initial symptom. Eight years earlier she had been treated for acute lymphocytic leukemia with cytotoxic treatment and radiotherapy, which had resulted in complete remission. She was first treated with an anticonvulsant because the atypical absence attacks and the presence of epileptic discharges on an EEG suggested epilepsy. However, with this mode of treatment the epileptic discharges did not disappear, but periodic high-voltage slow-wave complex discharges were revealed on subsequent EEGs. The antibody titer for measles virus in the cerebrospinal fluid and serum was elevated, confirming the diagnosis of SSPE. SSPE may arise, though rarely, in an individual in an immunosuppressive state due to congenital immunodeficiency or various kinds of malignancies, and also may arise several years after the contraction of measles infection. Our patient, however, lacked a past history of measles infection or immunization, suggesting the possibility that she had contracted measles during or shortly after the course of treatment for ALL.

Adolescent↗
PubMed1990

[A case of Aicardi syndrome with moderate psychomotor retardation].

A five-year-old girl of Aicardi syndrome showed moderate psychomotor retardation. She could walk and communicate. At six months of age, she developed salaam convulsion with series. Convulsions disappeared immediately after ACTH treatment. At eighteen months of age, she developed myoclonic seizures. From three years of age, head-nodding seizures with series relapsed and could not be controlled. But she could walk alone at two years old and speak a word at one and half years old. A degree of her psychomotor retardation was more slightly than others published cases of Aicardi syndrome. There were eleven reports, included our case, with mild retardation in Aicardi syndrome. The features of these are 1) late onset of seizures, 2) good response to ACTH therapy, 3) no significant abnormalities of brain except for agenesis of corpus callosum.

Adrenocorticotropic Hormone↗
PubMed1990

[CT findings of the temporal bones in Waardenburg's syndrome].

We reported three cases of Waardenburg's syndrome and discussed CT findings of the temporal bones. Two cases of these patients were mother and daughter. Case 1, a two-year-old girl, had lateral displacement of the medial canthi, a broad nasal root, hetero-chromic iridis, left ptosis, albinotic fundus, and bilateral congenital deafness. CT findings of the temporal bones showed enlarged vestibules, short lateral semicircular canal, and absent right posterior semicircular canal. The mother had congenital deafness, heterochromia iridis, and a white forelock and showed similar abnormal CT findings of the temporal bones. Case 2, a one-year-old boy, had lateral displacement of the medial canthi, a broad nasal root, partial heterochromia iridis, albinotic fundus, and bilateral congenital deafness. CT findings of the temporal bones showed enlarged vestibules and absence of semicircular canals except the right lateral semicircular canal. These cases were diagnosed as Waardenburg's syndrome on the basis of the characteristic features.

Abnormalities, Multiple↗
PubMed1987

Primary segmental demyelination in the sural nerve in Cockayne's syndrome.

In a typical case of Cockayne's syndrome, morphometric histopathologic findings of the sural nerve were described and compared with data on two controls. The main pathologic changes of myelinated fibers were segmental demyelination and remyelination with onion bulb formation and a moderate decrease of myelinated fibers. There was no evidence of axonal atrophy in relation to myelin spiral length. In addition, no evidence of the clustered occurrence of demyelinated and remyelinated internodes was obtained on the statistical evaluation of the distribution of such internodes. Although the presence or absence of hypomyelination of a mild degree and maldevelopment of axons to be myelinated has not been clarified, our morphometric data do suggest the presence of primary segmental demyelination of the biopsied sural nerve.

Biopsy↗
PubMed1987

Relationship between maturation of the skin and electrical skin resistance.

In 16 newborn infants (24 6-39 wk 6 days 830-3390 g) at ages between 0-70 days, the skin's electrical resistance was measured. Over 30 min we sequentially measured direct current resistance between two skin electrodes placed on the abdomen. The resistance was found to be low in very premature infants with gestation ages of 30 wk or less. It increased with both gestational age and postnatal age. In these infants, the resistance measured at 30 min during the first 4 days of life (3.4 +/- 0.3 K omega; mean +/- SD) was significantly less than that found at 20-70 days (8.8 +/- 1.2 k omega; p less than 0.001). The relationship between the infant's electrical skin resistance (y) and the gestational age (x) best fit the exponential formula: y = 7.42 X e0.24x X 10(-4) + 2.74. This formula shows that the electrical skin resistance increases exponentially during the last trimester. The measurement of electrical skin resistance is a quantitative method that can be utilized to evaluate the gestational age of infants.

Galvanic Skin Response↗
PubMed1986

Brainstem auditory evoked potentials in children with neurodegenerative diseases.

We assessed the usefulness of brainstem auditory evoked potentials (BAEPs) for differentiating types of degenerative diseases in children. The findings of BAEPs were abnormal in one out of two with polioencephalopathies and in seven of the eight with leukoencephalopathies, showing prolonged interpeak latencies of waves I-III, I-V or disappearance of wave components. On the other hand, normal responses were observed in four with corencephalopathies and one with spinocerebellopathy. The serial BAEPs in eight patients had deteriorated with progression of the clinical symptoms. These data on 16 children suggest that BAEPs are indeed a useful tool for monitoring pathophysiologic processes of neurodegenerative diseases.

Adolescent↗
PubMed1984

Is the F wave elicited in a select group of motoneurons?

The F wave represents only a small percentage of the motoneuron pool invaded antidromically by any single impulse. We studied 22 median nerves from 11 healthy subjects to determine whether the recurrent discharges are preferentially generated in a select group of motoneurons with certain physiologic characteristics. Partial excitation of the nerve elicited the F wave with no consistent bias toward either the lower or higher threshold motor fibers. When the fast conducting axons were progressively blocked using a collision technique, the F wave continued to appear in the remaining slow conducting axons which escaped the collision. We conclude that the recurrent discharges occur in approximately 1% of antidromically activated motoneurons irrespective of their peripheral excitability or conduction characteristics.

Anterior Horn Cells↗
PubMed1984

Stationary peaks from a moving source in far-field recording.

In 20 radial nerves, referential recording of antidromic sensory potentials from the digits consisted of two stationary far-field peaks, PI-NI and PII-NII. When compared with a bipolar recording of a moving source, the onset of PI and PII was coincident with the sensory potential approaching the wrist and the base of the digit, respectively. Of the two stationary positive peaks, PI was identical in latency irrespective of the digits tested. In contrast, the latency of PII was smaller for the first digit than the others, reflecting different distances from the stimulus point to the base of the respective digit. The amplitude of PII was proportional to that of the propagating sensory nerve action potential recorded at the volume conductor junction. A bipolar recording registers a near-field potential over the sensory fibers along the length of the nerve. In contrast, a referential recording represents a mixture of the near- and far-field potentials with the latter frequently producing major alterations of the classical triphasic wave. The standing far-field peaks show a temporal relationship to the traveling volleys approaching the main borders of the volume conductor. At the moment the sensory impulse reaches the boundary, current density changes suddenly in the two adjacent conducting media, giving rise to an apparent standing potential. The same mechanism probably plays an important role for the generation of some of the short latency peaks in the scalp recorded SEPs.

Action Potentials↗
PubMed1983

Field distribution of antidromically activated digital nerve potentials: model for far-field recording.

In 20 median nerves, the shift in mean latency of the referentially recorded antidromic sensory potential was 0.22 to 0.38 msec per 1.5 cm across the palm and only 0.03 to 0.05 msec per 1.5 cm along the third digit. In five radial nerves, referential recording from the tip of the second digit detected a stationary positive potential that was coincident with the entry of the sensory impulse into the nerve terminal near the base of the digit. These findings are consistent with the view that, in far-field recording of a traveling impulse, a time peak could result from an abrupt change in current flow that is based on the geometry of the volume conductor without fixed neural discharges.

Adult↗