Biomedical subjects
Publications and source records attributed to A Molster.
Six cases of fracture of the lateral part of the distal tibial epiphysis are presented. Five were operated on and 1 was treated with a plaster cast only. The results were excellent, and we advocate operative treatment of this fracture if more than minimal dislocation exists.
Gastric mucosal erosions were produced in rats by pyloric occlusion and intraperitoneal injection of epinephrine. Gastric ulcer was induced by the application of acetic acid to the anterior wall of the stomach. The gastric lesions were photographed and examined microscopically. 5 h after pyloric occlusion alone, the gastric mucosa looked essentially normal. After pyloric occlusion and injection of epinephrine, superficial mucosal erosions were observed in the major portion of the fundus. The presence of an acute acetic ulcer was found to inhibit partly or completely the development of mucosal erosions usually induced by pyloric occlusion and injection of epinephrine. It is suggested that this might be due to a local release of inflammatory mediators around the ulcer.
Explore the source record for details and available documents.
Explore the source record for details and available documents.
Gastric ulcer was induced in rats by application of acetic acid to the anterior wall of the stomach. Leakage of circulating albumin into the gastric wall was estimated by intravenous injection of radioactive albumin and determination of the radioactivity in different samples of the stomach wall. The protein leakage was found to be markedly increased in the anterior wall of the stomach, the increase being most pronounced close to the ulcer. The leakage remained fairly constant during the first 10 h of the experiment. The protein content of the posterior wall was about the same as in animals on which a sham operation had been performed. The protein leakage was associated with considerable oedema formation. The protein leakage indicates that inflammatory mediators are released in a wide area around the ulcer. The present experimental model offers an opportunity to find out which mediators are involved in the lesion.
Primary prosthetic replacement in elderly patients with displaced intracapsular fracture of the femoral neck has been used during the last few years with encouraging early results. The prosthetic device preferred has been Christiansen's endoprosthesis. During the past year a new type with separable plastic head and metallic cap has been used. This modification has resulted in the occurrence of a previously unknown complication, a separation of these two parts, necessitating reoperation and insertion of a new head piece. The possible mechanisms causing this separation are discussed.
No reliable treatment to reverse severe ergot-induced vasopasm is available. A case of ergotamine-induced vasospasm of the lower extremities is presented. A combined treatment of vasodilators, infusion of low molecular dextran and high epidural anaesthesia apparently prevented extremity gangrene from occurring.
Explore the source record for details and available documents.