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Biomedical subjects

A Monsaingeon

Publications and source records attributed to A Monsaingeon.

At least 19 recordsLinked to original sources

Wound healing. Comparison of healing rates of burn wounds and of excisional wounds.

The process of healing of skin excisions and skin burns of equal sizes has been compared in rabbits. Excisions heal definitely quicker than burns, despite the fact that the part of the skin exposed to the burning agent does not undergo necrosis. Small excisional wounds heal more rapidly than larger ones but the healing rate of burn wounds in our series was independent of their size. Secondary excision of the burned tissue accelerates the healing process. Thus the healing time of burn wounds seems to depend more on clearing the wounds of the necrotic tissue than on the mere repair of the skin loss.

Animals

Platinum electrode potentials and blood redox balance in the kidney during renal ischemia.

Potentials recorded with a platinum electrode inserted in the cortex and in the medulla of the right kidney "in situ" were compared with the log (Pyruvate)/(Lactate) in the arterial blood and in the blood of the right renal vein, during clamping of the entire pedicle or the renal vein alone. There is no correlation between potentials and log (P)/(L) when the renal blood flow is unimpeded. The medullary potentials correlate with the log (P)/(L) in the renal vein at the time of the removal of the clamp after clamping of the renal vein alone. There is a close correlation between the changes of tissue potentials and the changes of log (P)/(L) in the renal vein between the initial values and values at the time of the removal of the clamp. Thus, it seems possible to estimate by continuous electrical recordings the state and variations of the oxido-reduction balance of a tissue "in vivo".

Animals