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Biomedical subjects

A Morbidelli

Publications and source records attributed to A Morbidelli.

At least 19 recordsLinked to original sources
PubMed2005

Origin of the orbital architecture of the giant planets of the Solar System.

Planetary formation theories suggest that the giant planets formed on circular and coplanar orbits. The eccentricities of Jupiter, Saturn and Uranus, however, reach values of 6 per cent, 9 per cent and 8 per cent, respectively. In addition, the inclinations of the orbital planes of Saturn, Uranus and Neptune take maximum values of approximately 2 degrees with respect to the mean orbital plane of Jupiter. Existing models for the excitation of the eccentricity of extrasolar giant planets have not been successfully applied to the Solar System. Here we show that a planetary system with initial quasi-circular, coplanar orbits would have evolved to the current orbital configuration, provided that Jupiter and Saturn crossed their 1:2 orbital resonance. We show that this resonance crossing could have occurred as the giant planets migrated owing to their interaction with a disk of planetesimals. Our model reproduces all the important characteristics of the giant planets' orbits, namely their final semimajor axes, eccentricities and mutual inclinations.

Journal Article↗
PubMed2005

Chaotic capture of Jupiter's Trojan asteroids in the early Solar System.

Jupiter's Trojans are asteroids that follow essentially the same orbit as Jupiter, but lead or trail the planet by an angular distance of approximately 60 degrees (co-orbital motion). They are hypothesized to be planetesimals that formed near Jupiter and were captured onto their current orbits while Jupiter was growing, possibly with the help of gas drag and/or collisions. This idea, however, cannot explain some basic properties of the Trojan population, in particular its broad orbital inclination distribution, which ranges up to approximately 40 degrees (ref. 8). Here we show that the Trojans could have formed in more distant regions and been subsequently captured into co-orbital motion with Jupiter during the time when the giant planets migrated by removing neighbouring planetesimals. The capture was possible during a short period of time, just after Jupiter and Saturn crossed their mutual 1:2 resonance, when the dynamics of the Trojan region were completely chaotic. Our simulations of this process satisfactorily reproduce the orbital distribution of the Trojans and their total mass.

Journal Article↗
PubMed2005

Origin of the cataclysmic Late Heavy Bombardment period of the terrestrial planets.

The petrology record on the Moon suggests that a cataclysmic spike in the cratering rate occurred approximately 700 million years after the planets formed; this event is known as the Late Heavy Bombardment (LHB). Planetary formation theories cannot naturally account for an intense period of planetesimal bombardment so late in Solar System history. Several models have been proposed to explain a late impact spike, but none of them has been set within a self-consistent framework of Solar System evolution. Here we propose that the LHB was triggered by the rapid migration of the giant planets, which occurred after a long quiescent period. During this burst of migration, the planetesimal disk outside the orbits of the planets was destabilized, causing a sudden massive delivery of planetesimals to the inner Solar System. The asteroid belt was also strongly perturbed, with these objects supplying a significant fraction of the LHB impactors in accordance with recent geochemical evidence. Our model not only naturally explains the LHB, but also reproduces the observational constraints of the outer Solar System.

Journal Article↗
PubMed2001

Dynamical spreading of asteroid families by the Yarkovsky effect.

The orbital distributions of prominent asteroid families are thought to be direct by-products of catastrophic disruption events among diameter D greater, similar 100 kilometer bodies. Ejection velocities derived from studying observed families, however, are surprisingly high compared with results from impact experiments and simulations. One way to resolve this apparent contradiction is by assuming that D less, similar 20 kilometer family members, since their formation, have undergone semimajor axis drift by the thermal force called the Yarkovsky effect. Interactions between drifting family members and resonances can also produce unique eccentricity and/or inclination changes. Together, these outcomes help explain (i) why families are sharply bounded by nearby Kirkwood gaps, (ii) why some families have asymmetric shapes, and (iii) the curious presence of family members on short-lived orbits.

Journal Article↗
PubMed2000

Understanding the distribution of near-earth asteroids

We have deduced the orbital and size distributions of the near-Earth asteroids (NEAs) by (i) numerically integrating NEAs from their source regions to their observed orbits, (ii) estimating the observational biases and size distribution associated with asteroids on those orbits, and (iii) creating a model population that can be fit to the known NEAs. We predict that there are approximately 900 NEAs with absolute magnitude less than 18 (that is, kilometer-sized), of which 29, 65, and 6% reside on Amor, Apollo, and Aten orbits, respectively. These results suggest that roughly 40% of the kilometer-sized NEAs have been found. The remainder, on highly eccentric and inclined orbits, are more difficult to detect.

Journal Article↗
PubMed1998

Origin of multikilometer earth- and mars-crossing asteroids: A quantitative simulation

Orbital dynamic simulations show that many asteroids in the main asteroid belt are driven toward Mars-crossing orbits by numerous weak mean motion resonances, which slowly increase the orbital ellipticity of the asteroids. In addition, half of the Mars-crossing asteroids (MCAs) transition to Earth-crossing asteroids (ECAs) in less than 20 million years. This scenario quantitatively explains the observed number of large ECAs and MCAs.

Journal Article↗
PubMed1995

[Aneurysm of the iliac artery].

The authors consider isolated iliac artery aneurysms. While the incidence of isolated iliac lesion is, as literature reports, quite low, it rises up to 20% when associated with aortic lesions. The clinical findings are often characterized by effects of compression on the intrapelvic structures, by neurological symptoms and decreased venous flow. Diagnosis is based on ecography, CT and angiography for the definition of side and extension of the aneurysmatic lesion. From the technical point of view, the surgical approach is based on the dimensions of aneurysm and its mono- or bilateral extension. The most common approach in case of bilateral aneurysms or aorto-iliac lesions is transperitoneal, while it's limited to extraperitoneal way, when isolated iliac lesion. If the aneurysm involves the hypogastric artery, mostly when bilateral, the risk of bowel ischemic complications becomes more significative.

Aged↗
PubMed1995

[Bilateral thrombosis of a femoral pseudoaneurysm].

One case has been described of acute thrombosis of bilateral femoral anastomotic pseudoaneurysm. The clinical finding of bilateral acute ischemia of the lower limbs required urgent surgical treatment. The operative technique consisted of excision of anastomotic aneurysms and replacement by a new segment of prosthesis with an end-to-end anastomosis to the deep femoral artery. Pathogenesis of the pseudoaneurysms at the femoral anastomosis generally recognized numerous factors such as mechanical, graft or suture defects, hypertension, wound complications. Recognition of femoral anastomotic aneurysms is usually simple, when a pulsative mass is noted. In such a case (reported) of thrombosis of bilateral femoral pseudoaneurysms, preoperative diagnosis was more difficult. Anastomotic aneurysms of little size that occur later after original intervention require observation by echography and angiodinography. When rapid enlargement arises, urgent surgical treatment is required, before rupture or thrombosis. The surgical intervention consists of excision of the anastomotic aneurysm and replacement by a new segment of prosthesis between the prosthesis and the common or deep femoral artery. If the reconstruction at the level of femoral artery is not possible, the anastomosis is performed more distally, at the level of popliteal artery. The results are affected by the degree of urgency of surgery, with significant difference in favour of the patients Who underwent elective procedures.

Anastomosis, Surgical↗
PubMed1994

[Emergency surgery in patients over eighty].

The authors describe a series of 139 over-eighty patients (M = 53, F = 86), who underwent emergency surgery between 1-1-1987 and 30-6-1993. They consider diagnosis, copathology, type of surgical procedures, postoperative complications and final results. In this series they study 73 large bowel obstruction and 48 peritonitis. They notice important copathologies in 78% of patients, in particular cardiovascular diseases. They performed 74 mayor surgical procedures with 48% of postoperative complications and exitus in 24% of cases, due overall to exacerbation of coexisting diseases. The authors underline the direct between mortality rate and number of copathologies, and analyze the basic rules to follow in surgical indications and during the postoperative period.

Age Factors↗
PubMed1993

[Caustics-induced lesions of the gastrointestinal tract].

Ingestion of a corrosive agent results in a life-threatening clinical condition that requires emergency intensive care and often surgical intervention. Treatment is multifactorial and varies with the extent and depth of the injury. We report a case of a young 24-year-old man with accidental ingestion of sulphonic acid. After 1 month he developed a progressive dysphagia. Early endoscopic examination showed grade III injury to both the esophagus and stomach with severe and undilatable stricture of the antrum. Therapy included total parenteral nutrition and antibiotics. Repeat endoscopic examinations on days 30 and 40 showed progressive healing of the esophageal injuries, but confirmed a complete antral stenosis. After two months a large antecolic jejuno-gastroplasty was performed on the anterior wall of the stomach. The postoperative course was regular, and endoscopic examination showed complete healing of the injuries.

Adult↗
PubMed1991

[Thrombectomy of the infra- and suprarenal cava to prevent pulmonary embolism in the presence of deep venous thrombosis. Personal experience with 11 surgically-treated cases].

DVT is a fairly frequent event and often fails to be recognised. Its main complication, pulmonary embolism, is the third cause of death in Italy with more than 70,000 deaths per annum. In the presence of infra- and suprarenal floating thrombi, cases in which the application of neither intraluminal nor extraluminal filters is indicated, the treatment of choice is thrombectomy with direct surgical access to the cava. Personal experience of 11 patients operated in the past 16 months with excellent surgical success is analysed. The indications and surgical techniques adopted are described.

Adult↗
PubMed1990

[Use of a new anti-inflammatory drug in the treatment of varicophlebitis of the lower limbs].

The paper reports the results obtained in 20 patients affected by varicophlebitis of the lower limbs following the oral administration of an anti-inflammatory substance. Results were compared with findings in single-blind study performed in a group of 20 patients treated with placebo. The evaluation of residual signs and symptoms and the control of recanalization of venous collectors using Doppler tests revealed a difference between the two groups in favour of the patients treated with the anti-inflammatory agent, although this was not statistically significant. The use of the drug was considered useful as a support to conservative varicophlebitis therapy with the aim of accelerating the resolution of the inflamed condition and thus reducing the functional disability of the limb.

Administration, Oral↗
PubMed1990

Acute renal failure due to acute bilateral renal artery thrombosis: successful surgical revascularization after prolonged anuria.

Acute bilateral renal artery thrombosis is a rare but surgically correctable cause of acute renal failure. A middle-aged woman with acute renal failure and anuria due to atherosclerotic occlusion of the abdominal aorta and both renal arteries was surgically treated 42 days after the onset of anuria. Revascularization resulted in the reversal of renal failure and complete recovery of renal function in spite of prolonged anuria. An aggressive diagnostic and therapeutic approach is important whenever this condition is suspected.

Acute Kidney Injury↗
PubMed1989

[Protection systems of erythrocytes during intraoperative autotransfusion. Experience with the use of S-adenosyl-L-methionine].

An experiment lasting 2 years in more than 200 patients in single blind conditions (S-Adenosyl-L-Methionine vs placebo) aimed to improve protection of red cells during intraoperative autotransfusion. The two groups are analysed and, on the basis of objective hematochemical data it is concluded that in patients treated with the pharmacological support erythrocyte membrane stability is good.

Blood Transfusion, Autologous↗
PubMed1989

[Aneurysm of the popliteal artery: clinical aspects and therapy].

Experience of the operative treatment of 45 popliteal aneurysms in 41 patients is reported. The importance of immediate surgical reconstruction whenever a popliteal artery aneurysm has been detected is stressed. In fact, the patency rate of the arterial substitutes which are utilised in the reconstructive technique, and therefore the fate of the affected limbs, is chiefly based on the presence of a sufficient run off. Ischaemic complication due to peripheral embolization or sudden thrombosis of the aneurysmatic sac is very often followed by the irreversible closure not only of the tibioperoneal arteries but also of most collateral vessels.

Aneurysm↗
PubMed1989

[Loco-regional complications in the surgery of the subclavian artery].

Surgical treatment of subclavian artery atherosclerotic lesions has prophylactic significance in the evolution of cerebrovascular insufficiency. Local complications during interventions on subclavian artery are incidentally more significant than cerebral ischemic complications. Among local complications we reported 2 cases of phrenic nerve involvement and 1 case of thoracic duct lesion in a series of 86 operated patients. We never found cerebral ischemic complications in the surgery of subclavian artery atherosclerotic lesions.

Arteriosclerosis↗