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Biomedical subjects

A Morini

Publications and source records attributed to A Morini.

At least 37 records · Page 2Linked to original sources
PubMed1988

[Antiemetic protocol in oncohematologic polychemotherapy].

Authors, in an open and preliminary study, evaluate the beneficial effects on chemotherapy-induced nausea and vomiting of an association of three antiemetic drugs parenterally administered. Twenty-six patients receiving chemotherapy for Lymphomas (195 cycles) were treated with: Chlorpheniramine maleate 10 mg IM 45' before, Sulpiride 200 mg in normal saline 100 ml, at XXX gtt/m', 20' before, and 6-Methyl-Prednisolone 500 mg IV over 2'-3' immediately before chemotherapy. Patients were evaluated for emesis over 48 hours after chemotherapy: they were interviewed on nausea, vomiting and other possible side-effects. The antiemetic activity observed was: complete response in 73.1% (19/26); partial response 27.9% (7/26). Failure of response was never observed. 166/195 cycles were well tolerated. Our results demonstrate the antiemetic efficacy of this antiemetic regimen. Further studies should investigate its use in randomized trials.

Adult↗
PubMed1986

Spontaneous abortion in relation to the presence of hexachlorobenzene in the Italian environment.

This study determined hexachlorobenzene (HCB) levels in the blood of women who had suffered spontaneous abortions (120 cases) and women with healthy reproductive functions (120 controls). Samples were collected in 1984 during an epidemiological investigation into the relation between polychlorobiphenyl levels in the blood and spontaneous abortion in the women. Evaluation of the HCB data showed no significant differences between the groups, the blood of the group with spontaneous abortion containing 1.6 +/- 1.6 ppb HCB compared with 1.5 +/- 1.1 ppb for the control group.

Abortion, Spontaneous↗
PubMed1985

[A small epidemic focus of pulmonitis caused by Legionella].

A mini-epidemic consisting of 5 cases of Legionnaire's disease treated during september 1983 is reported. These patients shared many of the symptoms distinguishing the most common form of this disease in its severe or very severe form and some characteristic features of this case series are emphasised. It was impossible to trace the source of the outbreak, in spite of the fact that the mini-epidemic took place in an open situation. It is underlined that diagnosis is mainly clinical. The Legionella pneumophila bacteria should always be considered as one of the causal agents of bronchopneumonia, particularly when the following conditions are fulfilled: a) the disease takes the form of a confined, out-of-season, mini-epidemic; b) it is accompanied by multisystemic symptomatology and/or much greater involvement of general conditions that is usually to be expected in normal cases of bronchopneumonia. Since the disease is often fatal, erythromycin or rifampicin treatment should be started upon the slightest suspicion of contagion.

Adolescent↗
PubMed1984

[Psychosomatic disorders considered from an internist viewpoint. II. Problems of drug therapy].

Following a previous communication concerning some of the principal diagnostic and differential diagnostic questions regarding psychosomatic pathology, with the present note the authors wish to review the most common therapeutic problems related to these disorders. The text has been subdivided into two parts. In the first part it has been adjusted the approach to the pharmacological treatment of these disorders, following principally the authors' experience, and, in the second, have been analyzed some of the most common prejudices that have taken shape around this therapeutic praxis and that have contributed so much to handicap the diffusion of antidepressants in general practice. The authors conclude providing some clues both to those who, encouraged by the reading of this paper, should feel persuaded to deal with psychosomatic disorders from the general practitioners' point of view and to those who, for any reason, should not feel to tackle this task.

Amitriptyline↗
PubMed1984

[Psychosomatic disorders considered from an internist viewpoint. I. Nosographic aspects and diagnostic problems].

After a brief introduction regarding the nosography of psychosomatic disorders and the main reasons that have little by little discouraged non-psychiatric physicians to deal with this type of pathology, considering its high incidence among all the areas of general practice, the Authors go on discussing the diagnostic problems and pointing out the most important aspects concerned with these. The Authors conclude by warning not to over-value the effects obtained with an antidepressant especially when it is set up only on the basis of the ex-juvantibus principle. The Authors also invite their colleagues general practitioners to take greater care in the fight for prevention and treatment of these disorders, side by side with the psychiatrist.

Antidepressive Agents↗
PubMed1984

[Role and importance of antidepressants in general medicine. Bibliographic review and case contribution].

Starting from the consideration that communications relating to antidepressant drugs are chiefly reported by psychiatrists and that such reports deal with cases that we don't find in general practice, or at least marginally, the authors go on considering again their material consisting of 944 patients treated with antidepressants alone or associated with tranquilizers and/or with neuroplegic sedatives, hoping to gather usefull informations for a better definition of the role of these drugs in this large nosographic area. The authors could, therefore, by that way: confirm the high incidence of psychosomatic disorders among all the professional areas concerned with general practice; confirm the clear prevalence of the less symptomatic forms; verify in a high percentage of cases the coexistence of an organic disorder in way of progress or in outcome; confirm the double role of these drugs, diagnostic (ex-juvantibus) and therapeutical; suggest a third role of nosographic nature.

Antidepressive Agents↗
PubMed1984

[Irritable colon and psychosomatic disease].

The authors, after having considered the close likeness between the collateral clinical picture described by others in regard to the irritable colon syndrome and the outstanding one pointed out by them in many cases of psychosomatic disorders, have analyzed again a large number of personal cases diagnosed as "psychosomatic" in order to find possible relations between these two unwholesome conditions. At the end of their examination, after having ascertained that the "Irritable colon" has not to be considered an isolated disease but a syndrome caused by many factors, hinged on a predisposing condition likely of constitutional nature, the authors remark how it may nest in the folds of a psychosomatic disorder and sometimes be its outbreaking feature. The authors by this way, don't want to conclude identifying the I.C. with a psychosomatic disorder and suggest that in such cases one may take this syndrome as the main manifestation of a condition marked by an impairment of the digestive tract motility inside a psychosomatic disorder with a somatic expression of this apparatus.

Antidepressive Agents, Tricyclic↗
PubMed1982

[Secretory lymphomas].

After a short introduction regarding the concept of "secreting" lymphoma and the most recent theories about the dynamics of normal and pathologic lymphocytes, resulting from the actual immunologic advancements and designed in order do give an explanation of some of the problems concerned with these diseases, such as "classification", "transmutation" of one type of lymphoma into another and the lymphoma/leukemia question, the authors go on describing few personal cases taken as examples. Finally, upon having pointed out that following now a day's whole population screening there is an always more increasing number of asymptomatic "secreting" lymphomas, casually diagnosed, the authors call the general practitioners' attention on the most common clinical and laboratory features that should lead to suspect a lymphoma of this type.

Aged↗