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Biomedical subjects

A Mortada

Publications and source records attributed to A Mortada.

At least 19 recordsLinked to original sources

Histology of vitreous in its gel and fluid forms.

Low- and high-power microscopic examination of just-dried (without flame) fresh smears of gel, semi-gel, and fluid human and rabbit vitreous without stain showed that solid gel vitreous is composed of two types of transparent network, i.e., thick fibers in meshes of which there is another fine fibril network and both types of fluid vitreous, the fiber and fibril networks, show stages in transformation to transparent granules; this is why fluid vitreous remains transparent.

Animals

Chemical vitrectomy: change of solid gel vitreous to sol for vitrectomy by changing pH of vitreous toward the slight acid side.

Solid gel vitreous was changed to sol by changing the pH of the vitreous toward the slightly acid side by using diluted acetic acid of various weak concentrations. For human and rabbit vitreous in vitro, the gel sol change with regard to time in respect to concentration of the weak acid was noted. Rabbit eyes in vivo were used. In vitro and in vivo complete change of gelly vitreous to sol was achieved in about one hour by use of 0.3 mL of 0.5% acetic acid without any effect on the retina, choroid, optic disc, or the lens. This chemical vitreous fragmentation for vitrectomy was tried successfully on human eyes using 0.5 mL of 0.5% acetic acid without any bad effect in cases of vitreous hemorrhage not clearing in two months, posterior perforating injuries, and before cutting vitreous bands. A simplified method for pars plana irrigation drainage of liquid or chemically liquefied vitreous is described.

Acetates

Lindner posterior vitreous fistula with senile cataract extraction for quick reformation of anterior chamber: indications, technique, and results.

Pars plana partial vitrectomy using Lindner posterior vitreous fistula was prophylactically used with senile cataract extraction in cases known to be liable for nonreformation of anterior chamber and gelly vitreous with perfect results as regards postoperative maintenance of anterior chamber aphakic depth. The combined operation is indicated in cases (1) if the other eye was lost through nonreformation of anterior chamber after a perfect senile cataract extraction; and (2) in very old patients with very shallow anterior chamber especially when there are other senile ocular changes such as flatter, thinner cornea, tendency for uveal vascular engorgement and exudations (after hypotony of operation), and bad wound healing. This is especially true in small hypermetropic eyes with small cornea. The technique of the combined operation is described.

Age Factors

The encircling Silastic 3 mm band without cautery in retinal detachment surgery.

Retinal detachment with tears can be cured by scleral buckling by synthetic material pressure retino-choroidopathy without cautery (diathermy, cryo- or photocoagulation) to tear edges on conditions: (1) To use the encircling Silastic 3-mm band (equatorial or oblique according to tear site) giving a permanent buckle. The segmental buckle may recede reopening the tear and its retino-choroidopathy effect may not be sufficient to seal the tear. (2) Not to evacuate the subretinal fluid leaving the ocular tension at end of operation a bit high [about 25 mm Hg in the first operation and 5 mm Hg (Schøtz) in the recent reoperation above the preoperative level]. The synthetic material pressure retino-choroidopathy seals the tear and lowers the ocular tension in subsequent days with beter buckling. (3) As these conditions may not be attained, it is wiser to use minimal diathermy or cryo-therapy to seal the tear.

Follow-Up Studies

Posterior unbuckled part of a giant tear behind the oblique encircling silastic 3 mm band operation. Surgical prevention and treatment.

(1) In operable giant tear extending slightly behind the equator, the oblique encircling silastic 3 mm band without evacuation of subretinal fluid gave a 70% success rate. In 30% of the cases a small most posterior part of the tear was seen unclosed behind the band effect. This was because of thick sclera opposite the tear area preventing proper buckling. (2) This gave an occasion to see during reoperation the effect of segmental silastic 5 mm rod buckling opposite the unclosed part of the tear. (a) Two rods placed radially between the band and the sclera opened the whole giant tear again. (b) One rod placed circumferentially behind the band succeeded in closing the unclosed part of the tear. (3) To have a sufficient wide buckle in cases of thick sclera opposite giant tears one of the best, safest and easiest solutions is to weaken the sclera behind the tear by incising about half scleral thickness opposite the anterior and posterior margins of the oblique band (or even lamellar scleral resection underneath the oblique band) in a wider area than the tear meridans extent (Mortada modified operation). This helps buckling at a lower band tightness, thus avoiding any complication of pressure uveopathy.

Humans