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Biomedical subjects

A Mortimer

Publications and source records attributed to A Mortimer.

26 records · Page 2Linked to original sources

Alleged shoplifters and psychiatric outpatients: drugs, absent-mindedness and mental state compared.

Thirteen shoplifters were found to fit into a new classification based on mens rea. When compared to an age and sex matched control group of new psychiatric outpatients there were no significant differences in psychiatric morbidity, drug impaired arousal, absent-mindedness and course of illness. There was evidence that absent-mindedness may be responsible for some alleged offences and that this may occur repeatedly.

Amnesia↗

Pseudocyesis preceding psychosis.

Pseudocyesis is an uncommon condition in which the psychological and somatic phenomena are usually thought to arise with neurotic rather than psychotic illness. We report a patient whose pseudocyesis took a course not previously described, culminating in an acute schizophrenic episode. Despite this she demonstrated many similarities with neurotic patients previously described in the literature. A phenomenological explanation, the belief of pregnancy as an overvalued idea, is discussed.

Adult↗

Thyroid function screening of psychiatric inpatient admissions: a worthwhile procedure?

A thyroid function screening programme of admissions to a general psychiatric service was established. Over a 22-week period 588 patients were admitted and thyroid function tests were performed on 336, a screening rate of 57.1%. Initial investigation showed that 21.3% had a total thyroxine outside the range 75-130 nmol/l. On further investigation only 9 patients (1 thyrotoxic, 8 hypothyroid) had confirmed thyroid disease. In 7 of the 9 patients the disease had been clinically suspected. Thus the screening programme identified only 2 unsuspected cases of thyroid dysfunction and we conclude that this level of detection does not warrant a formal screening programme.

Adult↗

Free radical production in amniotic fluid and blood plasma by medical ultrasound.

Evidence is reported that continuous wave and long pulse ultrasonic systems can induce relatively large amounts of free radicals in biological fluids in vitro under conditions similar to those currently in use for therapeutic applications. The operating conditions and approximate threshold intensities under which these instruments can produce free radicals are described.

Amniotic Fluid↗

An instrument for ultrasonic biometry.

A simple instrument has been developed for measurement of axial length and anterior chamber depth. It is pocket sized, and the digital output is easy to interpret. The long term accuracy of 0.2 mm is ideal in helping to eliminate errors of lens selection.

Anterior Chamber↗

A Canadian high-energy neutron spectrometry system for measurements in space.

Bubble Technology Industries Inc. (BTI), with the support of the Canadian Space Agency, has finished the construction of the Canadian High-Energy Neutron Spectrometry System (CHENSS). This spectrometer is intended to measure the high energy neutron spectrum (approximately 1-100 MeV) encountered in spacecraft in low earth orbit. CHENSS is designed to fly aboard a US space shuttle and its scientific results should facilitate the prediction of neutron dose to astronauts in space from readings of different types of radiation dosimeters that are being used in various missions.

Astronauts↗

Impact of side-effects of atypical antipsychotics on non-compliance, relapse and cost.

Atypical antipsychotics generally have milder side-effects than conventional antipsychotics, but also differ among themselves in this respect. This study aimed to compare the impact of different side-effect profiles of individual atypical antipsychotics on non-compliance, relapse and cost in schizophrenia. A state-transition model was built using literature data supplemented by expert opinion. The model found that quetiapine and ziprasidone were similar in estimated non-compliance and relapse rates. Olanzapine and risperidone had higher estimated non-compliance and relapse rates, and incremental, 1-year, per-patient direct costs, using US-based cost data, of approximately $530 (95% confidence interval [CI] approximately $275, $800), and approximately $485 (95% CI approximately $235, $800), respectively, compared with quetiapine. Incremental costs attributable to different side-effect profiles were highly significant. This study shows that differing side-effect profiles of the newer antipsychotic agents are likely to lead to different compliance rates, and consequent variation in relapse rates. The cost implications of these heterogenous clinical outcomes are substantial.

Antipsychotic Agents↗