[The surface finishing of surgical and dental implants (value and difficulties)].
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Alloys↗
Biomedical subjects
A Mosser
Publications and source records attributed to A Mosser.
Creation of an antigenic site in poliovirus type 1 by assembly of 14 S subunits.
Using a set of neutralizing monoclonal antibodies targeted against the four known antigenic sites of poliovirus type 1, it was shown that three out of four antigenic sites are already present on 14 S subunits (pentamers of the structural unit). Site 3B, in contrast, is formed upon assembly of 14 S subunits into capsids. The data support the hypothesis that site 3B spans the boundary between pentamers in the virion.
Antibodies, Monoclonal↗
Surface physics methods and in vitro bone-biomaterial interface control.
After a brief review of the main characteristics of some spectroscopic and microscopic methods for surface and interface analysis, preliminary and prospective studies of biocompatible materials (hydroxyapatite, alumina) for implant coating purposes are presented. The results show that the use of complementary techniques allows information on the physical and chemical properties of the coatings both on a microscopic and on an atomic scale to be obtained.
Aluminum Oxide↗
Biological control of Biomphalaria glabrata and B. straminea by the competitor snail Thiara tuberculata in a transmission site of schistosomiasis in Martinique, French West Indies.
In Martinique, intestinal schistosomiasis was discovered at the beginning of this century. The intermediate host snail, Biomphalaria glabrata, was considered in the past as a common species in the different habitats of the island, but during the last decade it has been found only in water-cress beds. Several of these water-cress cultures contained mixed populations of B. glabrata and B. straminea. Moreover, these habitats also constituted transmission sites for Schistosoma mansoni infection. In 1979 the thiarid snail Thiara ( = Melanoides) tuberculata was discovered in Madame river, Fort-de-France, and in the following years at other sites. In 1983 a programme of biological control using this snail was started in two groups of water-cress beds. In 1981-1982 the study site, Roxelane valley, sheltered important populations of B. glabrata (45-256 individuals/m2) and of B. straminea (2-30 ind./m2). In January 1983 the competitor T. tuberculata was introduced into the two groups of water-cress beds (1.3 and 1.7 ind./m2 respectively) and during subsequent years snail population sampling was carried out. The results showed rapid colonization by the competitor snail, whose densities reached 178 and 325 ind./m2 in November 1983 and a maximum of 9941 and 13,388 ind./m2 in October 1984. During that time, B. glabrata populations declined: 153 and 41 ind./m2 in November 1983, 4 and 0 ind./m2 in October 1984, and 0 ind./m2 in the two groups of water-cress beds in October 1985. A similar phenomenon was observed for B. straminea. Since October 1985 neither planorbid species has been found by exhaustive sampling of the habitats.(ABSTRACT TRUNCATED AT 250 WORDS)
Animals↗
[Acute rheumatic fever in Martinique. Epidemiological, clinical and biological study].
An epidemiological and clinical survey of rheumatic fever was carried out in Martinique. The clinical manifestations, portal of entry and socio-economic facilitating factors appeared to be the same as those observed in metropolitan France when the disease occurred with a similar frequency. The prevalence and severity of rheumatic fever in Martinique are still high (in 1982, 49 new cases in a population of 300,000, including 12 with severe carditis), but they tend to diminish as the eradication campaign goes on. The reasons for the persistence of the disease and the problems encountered in the eradication campaign are discussed in the light of epidemiological data collected during the last 3 years.
Adolescent↗
[Contraceptive hormones, vascular risk and abnormal precipitation of serum gamma-globulins (author's transl)].
The monoclonal anti-ethinyl-estradiol antibody previously found in the serum of a woman on oral contraceptives, was precipitated by 25% saturated ammonium sulfate à 22 degrees C. This simple test has been used to investigate the possible relationship between abnormally precipitating gamma-globulins (GAP) and the vascular risk of the pill. Four groups of women were studied: --50 women who had never used the pill; --100 women on oral contraceptives; --30 women who had stopped the pill; --17 women had experienced venous or arterial thrombosis during oral contraception. The results obtained indicate: 1) that a GAP increase is nearly always associated with the thrombotic events (90% of the cases in group 4); 2) that the presence of GAP is seen only in part of the women population on oral contraceptives representing approximately 30% of the total population investigated as indicated by a bimodal distribution. 3) that the GAP remain increased for months and even years after the pill was discontineud. The significance of this test is discussed. It is proposed that the presence of GAP in the serum appears to be related to the presence of ethinyl-estradiol binding antibodies. This hypothesis is verified by experiments in progress.
Adolescent↗
[Contraceptive hormones, vascular risk and abnormal precipitation of serum gamma-globulins (author's transl)].
The monoclonal anti-ethinyl-estradiol antibody previously found in the serum of a woman on oral contraceptives, was precipitated by 25% saturated ammonium sulfate à 22 degrees C. This simple test has been used to investigate the possible relationship between abnormally precipitating gamma-globulins (GAP) and the vascular risk of the pill. Four groups of women were studied: --50 women who had never used the pill; --100 women on oral contraceptives; --30 women who had stopped the pill; --17 women who had experienced venous or arterial thrombosis during oral contraception. The results obtained indicate: 1) that a GAP increase is nearly always associated with the thrombotic events (90% of the cases in group 4); 2) that the presence of GAP is seen only in part of the women population on oral contraceptives representing approximately 30% of the total population investigated as indicated by a bimodal distribution; 3) that the GAP remain increased for months and even years after the pill was discontinued. The significance of this test is discussed. It is proposed that the presence of GAP in the serum appears to be related to the presence of ethinyl-estradiol binding antibodies. This hypothesis is verified by experiments in progress.
Adolescent↗