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Biomedical subjects

A Muolo

Publications and source records attributed to A Muolo.

At least 19 recordsLinked to original sources

Small renal-cell carcinomas: clinical and imaging features.

The authors review the clinical, pathological and imaging characteristics of 20 patients with histological confirmation of 23 renal-cell carcinomas measuring < or = 3 cm in size. All lesions were unilateral. All patients were submitted to CT investigations, which identified 20 tumours (86%) and failed to identify 3 small-sized neoplastic nodular formations (0.4, 0.4, 0.8 cm) in patients with double tumour localisation in the same kidney. 15 patients underwent ultrasonography (US) which detected 11 carcinomas out of 17 (65%); of the 6 tumours (in 4 patients) not detected by US, 4 were identified by CT; 2 of these patients were subsequently re-examined by US with identification of the tumour. US failed to detect the 2 small tumours unidentified by CT (the third patient did not undergo US). 17 patients had no renal symptoms, and identification of the tumour was an incidental finding. The increasingly widespread use of US and CT enables a large number of kidneys to be examined and thus permits identification of a greater number of small-sized kidney tumours, allowing early surgical intervention with a greater chance of success. The technical options in surgical therapy may be multiple, though the use of any operation other than nephrectomy tends to be limited by the possible presence of small neoplastic nodular formations in the same kidney, which may not be detectable by US or CT owing to their very small size.

Carcinoma, Renal Cell

[Renal angiomyolipoma: diagnostic approach and therapeutic up-date; report of 11 clinical cases].

Eleven cases of renal angiomyolipoma are reported. In all cases a correct preoperative diagnosis was made, using standards x-radiography, ultrasonography and computerized tomography. Small size AML do not generally require any surgery, while surgical procedures for larger AML vary depending on the size, associated diseases, other complicating factors. As a general rule, surgical treatment should be as conservative as possible.

Adolescent

Thyroid metastases from renal carcinoma.

The identification and diagnosis of thyroid metastases from renal adenocarcinoma are rare in living patients, though more frequent during autopsy. A case is reported in which the identification of thyroid metastases indicated a clear-cell renal carcinoma in a kidney treated 12 years earlier for emptying of multiple cysts.

Carcinoma, Renal Cell

[Hyperparathyroidism in patients having undergone a kidney transplant].

The persistence or onset of hyperparathyroidism following kidney transplant is characterized by an incidence ranging from 2.6 to 70% according to the various statistics available. In a total of 462 kidney transplants performed in our department, hyperparathyroidism was detected in 9 patients. Surgery took the form of parathyroidectomy 8/8 plus autograft in 3 cases, parathyroidectomy 3/4 in 2 cases, 7/8 in 2 cases, and 4/8 in 1 case. Serum calcium values returned to normal in all patients after the operation.

Humans

[Malignant neoplastic pathology in patients given a kidney transplant].

The incidence of malignant neoplasms in patients subjected to pharmacological immunosuppression following kidney transplantation is higher than that observed in the control population at large. In our unit, in a study population of 451 patients undergoing a total of 462 kidney transplants over the period from 1968 to 1986, four malignant neoplasms (0.9%) were observed in 3/369 (0.8%) patients treated with azathioprine (1 ovarian papilliferous cystoadenoma, 1 embryonal carcinoma of the testicle and 1 Kaposi's sarcoma) and in 1/93 (1.1%) patients treated with cyclosporin (1 Kaposi's sarcoma). The neoplasm was successfully controlled only in the first case after bilateral extended adnexectomy.

Azathioprine

[Spontaneous perirenal extravasation of urine].

Perirenal urinary extravasation in the course of violent renal colic appears to occur much more frequently than is reported in the literature. In this study, the authors report on three such cases observed personally in the space of one year and discuss the pathophysiological factors which may give rise to this phenomenon.

Adult

[Adenomatoid tumor of the epididymis].

Primary tumors of the epididymis are very rare. The neoplasms most frequently affecting the epididymis are adenomatoid tumors. In this report, the authors describe a case observed personally. Various histogenetic hypotheses and the histological characteristics of the tumor are discussed.

Epididymis

[Primary retroperitoneal tumors (clinical findings in yolk sac tumor, vascular leiomyosarcoma and extraosseous chondrosarcoma)].

Primary retroperitoneal tumors (PRT) constitute about 0.02 per cent of all tumors examined in the Department of Pathology of our hospital. We report 3 cases of malignant PRT - yolk-sac tumour, vascular leiomyosarcoma and extraskeletal chondrosarcoma - selected for their histological rarity and clinical features. Recent techniques available for the diagnosis of these neoplasms and surgical treatment are discussed. The role of radio-chemotherapy is also dealt with.

Adult

[Adenoma nephrogenic. Morphologic aspects].

Nephrogenic adenoma is a rare lesion of urothelial mucous membrane. At present, the cases described in literature are 85. In this work the Authors study the morphologic aspects and etiopathogenetic theories.

Adenoma

[Desmoid tumors (apropos of a clinical case)].

The authors, starting from a case of desmoid tumour of abdominal wall, they had the opportunity to observe, discuss its possible etiopathogenetic factors, and confirm the validity of operation as the only therapy.

Abdominal Muscles

[Spontaneous rupture of the transplanted kidney].

The spontaneous breakage of a kidney is a rare complication which may occur in the first weeks after a transplantation. The cause which can determine it is not yet cleared up, although the Authors think the greatest responsibility for this can be ascribed to rejection. In this work the authors report the experience and casuistry of the Transplantation Centre of Verona.

Adolescent

[Lymphocele after renal transplant: considerations based on a clinical case].

The Authors study again the problems of lymphocele in kidney transplantation by showing an interesting clinical case: a lymphocele with smallest size, developing an intensively compressive action on iliac vein. In the light of the experience of 354 transplantations, they discuss the etiopathology and clinics thereof. They particularly emphasize the diagnostical role of echography. Whereas the asymptomatic lymphoceles require no treatments for their trend to be reabsorbed, the symptomatic ones need a quick solution of the compressive effect. Then they consider the therapeutical solutions suggested as an alternative to the interperitoneal marsupialization, which remains the most widely used method.

Adult

[Urologic complications in kidney transplants: experience in 274 transplants].

The urological complications after a renal transplantation still represent an event anything but rare, ranging, according to the different statistics, from 0.9% up to 23%, with a mortality between 0 and 25%. In this work done by the Verona Centre the experience on 274 transplantations is reported. The urological complications weighed with 6.2% and absence of mortality among the patients. The importance of the prevention and precocious diagnosis is confirmed.

Adolescent