Biomedical subjects
Publications and source records attributed to A Mysliwski.
The size and dry mass of erythrocytes from the blood of men of various ages were measured by means of microscopic interferometry. The donors age-dependent increase of erythrocytes size and dry mass was found.
Activity of (Na+,K+)ATP-ase measured by means of influx of 86Rb was compared in lymphocytes from young, middle-age and old people. It was found that the (sensitive to ouabain) activity of (Na+,K+)ATPase was significantly diminished in the lymphocytes from aged subjects.
The correlations between serum HDL, total cholesterol, triglycerides or free fatty acids levels and the percentage of human peripheral blood lymphocytes bearing receptors for SRBC, MRBC, Con A or sIgG were sought in the aged people. The persons examined showed a marked heterogeneity in their serum lipid levels as well as in the results of lymphocyte surface receptor analysis. However, the only correlation found was that between the percentage of MRBC-rosette forming cells and the level of serum free fatty acids. The total cholesterol level, known as the modulator of some physical parameters of lymphocyte membrane, had, in our examination, no correlation with the changes of surface properties of lymphocytes. The possible physiological role of the phenomena observed is discussed.
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