[Changes in activation marker expression by lymphocytes in patients with infectious allergic myocarditis associated with disease progression].
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Antigen-Presenting Cells↗
Biomedical subjects
A N Kazimirskiĭ
Publications and source records attributed to A N Kazimirskiĭ.
[Effect of tissue damage mediators on the expression of surface antigens by human lymphocytes in vitro].
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Adenosine↗
[Effect of peptide hydra morphogen on the structure of tissue components of rat myocardial layers in the early period of heart hypertrophy development].
The morphological study showed that the single injection of HMP (Hydra Morphogen Peptide) facilitated the development of the myocardium hypertrophy. This effect is expressed in the subendocardial layer most of all, where the normalization of the relative volume and diameter of the cardiomyocytes and the decrease of the connective tissue oedema are noted. These parameters are normalized in the intramural and subepicardial layers in less degree. The decrease of the connective tissue oedema is noted in the intramural layer. The normal correlation recovery between the relative volumes of the cardiomyocytes and the connective tissue is shown in the subepicardial layer, the diameters of the myocytes are essentially increased. The influence of HMP is manifested not only on the muscular and connective tissue components of the myocardium, but touches on also the system of the myocardial wall vessels, causing the redistribution of the intramural blood circulation.
Animals↗
[The dynamic changes in the tissue components of the myocardial layers under compensatory heart hypertrophy in exposure to a peptide hydra morphogen].
Morphometric analysis of the left ventricle myocardial layers under heart hypertrophy was carried out. Values of tissue parameters on the 3rd, 10th and 24th days after 50% coarctation of the abdominal aorta were received. Is shown the heart functioning under conditions of myocardial compensatory hypertrophy development is characterized by expressed zones and different directions of changes of quantitative parameters of tissue components. The single injection of HMP (Hydra morphogen peptide) made the development of myocardial hypertrophy easy at early stages, decreasing depth of manifestations morphologic changes and perhaps affected the time of their development.
Adaptation, Physiological↗
[Effect of low doses of the hydra peptide morphogen on protein biosynthesis in the intact and regenerating rat liver].
The dependence of ornithine decarboxylase (ODC) activity on hydra peptide morphogen doses has been established. The parameters of protein synthesis were determined in normal and regenerating rat liver, using the peptide in a dose of 20 micrograms/kg body weight, initiating maximum enzyme activity. It was established that intraperitoneal injection of the peptide in partially hepatectomized animals stimulated ODS activity in dose-dependent manner and was dome-shaped. The peptide injection in intact animals does not affect the intensity of 3H-leucine inclusion into the liver protein and the protein content in rat liver. However, the peptide injection in partially hepatectomized animals increased the level of 3H-leucine inclusion into the protein of regenerating liver and stimulated protein accumulation in this type of tissue.
Animals↗
[Modulation of ornithine decarboxylase activity in the normal and regenerating rat liver by different doses of hydra peptide morphogen].
The authors studied the anabolic effect of peptide morphogen of the hydra undecapeptide on normal and regenerating rat liver. Ornithine decarboxylase (EC 4.1.1.17) activity served as a marker. Intraperitoneal injection of the peptide into intact animals stimulated ornithine decarboxylase activity in a dose-dependent manner. In partially hepatectomized rats the peptide stimulated ornithine decarboxylase activity in the dose of 20 micrograms/kg body weight while greater doses inhibited the enzyme activity.
Animals↗
[Purification of cyclic nucleotide phosphodiesterase from the external segments of retinal rods; conjugation of the enzyme with an inhibitor].
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2',3'-Cyclic-Nucleotide Phosphodiesterases↗
[Immunodeficiency development in non-specific infectious inflammation].
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Anti-Infective Agents↗
[Mechanisms of immunotropic effect of the drug composition Taban-Arshan (Tibet medicine) on lymphocytes of patients with early rheumatoid arthritis and atopic bronchial asthma].
The extract of the Tibetan medicine Taban-Arshan corrects changes of the immune system in inflammatory diseases--rheumatoid arthritis and atopic bronchial asthma. An immunomodulating effect of the drug consists in its ability to suppress hyperactivation of lymphocytes by normalization of expression of basic activation antigens.
Adult↗