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Biomedical subjects

A N Korolevich

Publications and source records attributed to A N Korolevich.

3 recordsLinked to original sources

Investigation of blood flow microcirculation by diffusing wave spectroscopy.

This article presents a technique and a setup for noninvasive in vivo studies of cutaneous microcirculation. The technique is based on the analysis of intensity fluctuations of scattered coherent light. The analysis is made in terms of diffusing wave spectroscopy. The developed technique can be used in clinical practice to determine the motion pattern of scattering particles (such as red blood cells) in randomly inhomogeneous media (such as biological tissues). The average size of scattering particles can be comparable to the wavelength of scattered radiation.

Animals↗

Experimental study of the potential use of diffusing wave spectroscopy to investigate the structural characteristics of blood under multiple scattering.

The extension of the photon correlation spectroscopy (PCS) in multiple scattering regime, so-called diffusing wave spectroscopy (DWS) was employed to the study of blood samples. Multiple scattered light from a helium-neon (He-Ne) laser beam incident on the blood samples was detected by a photomultiplier, and both the temporal autocorrelation intensity functions g 2(tau) and power spectra S(omega) were measured by a spectrum analyzer. The potentials of using DWS for the qualitative and quantitative determination of the structural characteristics of the blood elements were studied experimentally. The experimental studies made, permits the use of DWS for blood cells monitoring in a multiple scattering regime. This paper describes our initial attempts at applying DWS to the study of the discrete blood samples of both healthy donors and patients with the cardiac ischemia. The subsequent experiments provide a verification of DWS of blood cells shape monitoring under multiple scattering.

Blood↗

[Changes in human biliary vesicle sizes in pathological states].

Changes in the sizes of aggregates of bile vesicles at various nucleation factors were studied by the method of dynamic spectroscopy. It was found that the sizes of bile vesicles in chronic cholecystitis vary from 90 to 200 nm. It was shown that the presence of a large fraction of bile vesicles characterized by a higher cholesterol concentration can serve as a criterion of acuteness of cholecystitis and the intensity of lithogenesis.

Adult↗