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Biomedical subjects

A N Litvinenko

Publications and source records attributed to A N Litvinenko.

At least 19 recordsLinked to original sources
PubMed2006

[Modern tendencies in diagnosis and treatment of an acute destructive pancreatitis].

The problem of an acute pancreatitis was one of "key" ones in investigations of A. A. Shalimov and his school. While the knowledge concerning the disease pathogenesis improved, diagnostic and treatment algorhythm elaborated, modern medicinal preparations and surgical treatment introducted, including miniinvasive technologies, so also approaches to treatment of patients, suffering an acute pancreatitis, have changed.

Humans↗
PubMed2004

[Simultaneous operations during laparoscopic cholecystectomy].

Simultant laparoscopic operations were performed in 1993-2003 yrs period in 321 patients, including 287--using laparoscopic and 34--the combined (laparoscopic and open) access. Concurrent diseases were diagnosed preoperatively in 219 (68.2%) of patients and were disclosed while doing intraoperative revision--in 102 (31.8%). The simultant operations performance, as a rule, enhanced mildly the total duration of a basic stage, did not influence the duration of postoperative period and the patients rehabilitation essentially, as well as for frequency of the intra--and postoperative complications occurrence. The authors consider that it is expedient to perform laparoscopic intervention simultaneously for concurrent surgical diseases of abdominal cavity.

Adolescent↗
PubMed2004

[Experimental substantiation of the method of biological tissue welding in surgical hepatology].

Application of the welding method for biological tissues in hepatobiliary surgery was experimentally substantiated. In 14 pigs (25-30 kg body mass) resection of one hepatic lobe, using electric welding method, was done. In control group (4 pigs) the similar operative intervention was accomplished, using conventional method. Application of the electric welding method guarantees secure hemostasis and cholestasis, do not causes specific pathological changes in the adjacent region of affection tissues, speed of restoration of the structures damaged exceeds such in application of the suturing method.

Animals↗
PubMed2002

[Experimental application of electrocautery in biliary surgery].

The testing of a new nonsuture electrothermic method of biliary system tissues connection was conducted in laboratory animals--rabbits and pigs. Reactions of tissues and cells in zone of electric influence and the gallbladder suture, remote reactive changes in the operation zone were studied up. In application of the proposed method of the regeneration processes inhibition and specific pathological changes in surrounding tissues were not noted, speed of the damage structure restoration was comparable with such in the tissues connection using suture materials.

Animals↗
PubMed2002

[Effect of spore-free anaerobic microorganisms of pancreatic tissue in experimental acute pancreatitis].

The simulation model of an acute pancreatitis (AP), using translocation of microorganisms from intestine to ductal system and pancreatic tissue, was created in experiment on dogs. Interrelationships between pancreatic tissue and anaerobic microorganism in an AP were studied, using electron microscopy. Possibility of the microorganisms migration to pancreas from ductal system in early stage of AP due to enhanced reproduction of anaerobic microorganisms in duodenum was established. It is impossible to exclude the possibility of their invasion via the lymph and the blood flow into destructively changed pancreatic tissue in late terms of the disease.

Animals↗
PubMed2001

[Application of electro-thermo-adhesion in hepatobiliary surgery].

Since 1999 yr. 283 laparoscopic operations were performed in the clinic for diseases of liver, biliary ducts, pancreas using electrothermoadhesion method, including 201 cholecystectomies, 62--in presence of hepatic cyst, 6--enucleation of hemangioms, 3--hepatic edge resection, 1--cholecystectomy, in 10 patients the puncture biopsy of pancreas was done.

Bile Duct Diseases↗
PubMed2001

[Lessons on laparoscopic cholecystectomy (summary of the experience].

The experience of laparoscopic cholecystectomy conduction in 6524 patients with nontumoral diseases of gallbladder (chronic calculous cholecystitis, an acute calculous cholecystitis, chronic noncalculous cholecystitis, the gallbladder polyposis) was summarized. While comparing the initial seizing experience in laparoscopic cholecystectomy in the clinic the tendency was noted, trusting the skills improvement in management of laparoscopic technique, permitting to reduce the contraindications quantity for laparoscopic cholecystectomy. Several principles were elaborated, which is necessary to follow doing laparoscopic cholecystectomy for improvement of results of treatment in patients and for complications reduction.

Adolescent↗
PubMed2001

[The meaning of interleukin-6 in chronic biliary pancreatitis].

The interleukin-6 (IL-6) contents in the blood serum and in bile from the gallbladder was studied in 25 patients with uncomplicated cholelithic disease and with that, complicated by chronic biliary pancreatitis. Laparoscopic cholecystectomy was done in all the patients. In uncomplicated cholelithic disease IL-6 was not revealed in the blood serum and in majority of observations--in bile from gallbladder. Direct dependence was established between duration of cholelithic disease existence, complicated by chronic biliary pancreatitis, and concentration of IL-6 in bile from gallbladder.

Adult↗
PubMed2000

[Laparoscopic interventions on choledochus: 5 year experience].

Complex examination of 69 patients with complicated cholelithic disease was performed. The elaborated in the clinic algorithm for preoperative examination of the patients was applied to reveal the main bile ducts pathology. Indications for the laparoscopic interventions on choledochus performance were substantiated.

Adult↗
PubMed1994

[Diagnosis of cancer of the pancreatic body and tail].

Results of 194 patients observation with cancer of corpus et cauda pancreatis are adduced. Clinical forms of the disease are distinguished. Rational algorithm for the examination of patients with probable cancer of corpus et cauda pancreatis diagnosis was elaborated grounded on the efficacy analysis of various methods of examination (ultrasonic investigation, computed tomography, endoscopic retrograde cholangiopancreatography, selective, angiography and so on). The algorithm application permitted to improve significantly the diagnosis of disease.

Adult↗
PubMed1993

[A rational procedure for the treatment of patients with chronic calculous cholecystitis complicated by choledocholithiasis].

The results of surgical treatment of 156 patients with chronic calculous cholecystitis complicated by choledocholithiasis have been analysed. In 62 patients, cholecystectomy in combination with choledocholithotomy was performed. Ninety four patients underwent additional drainage operations on the terminal common bile duct. Endoscopic papillosphincterotomy was performed in 90% of cases, other drainage interventions (choledochoduodenostomy and transduodenal papillosphincterotomy)--in 10%.

Cholecystectomy↗
PubMed1991

[Multimodal treatment of pancreatic cancer].

The experience with combined treatment of 122 patients with pancreatic cancer in the clinic of the Institute of Clinical & Experimental Surgery for the period of from 1988 to 1990 is summarized. Radical operations were performed in 54 patients, the palliative ones--in 68. After performance of a palliative operation, the patients underwent polychemotherapy, 5--in combination with UHF-hyperthermia. To study the effect of chemotherapy on the immune system, the immunologic monitoring was carried out. It was established that under the influence of chemotherapy and hyperthermia, the indices of immunity in patients with pancreatic cancer improved. In cancer of the pancreatic head with involvement of pancreatic body, the performance of subtotal pancreatoduodenal resection with subsequent regional chemotherapy is expedient. Chemotherapy and hyperthermia in combination with creation of a shunt permit to improve the results of treatment of inoperable tumors. The use of regional chemotherapy in subtotal resection contributed to increase in 2-year survival of the patients.

Antineoplastic Combined Chemotherapy Protocols↗
PubMed1990

[Reoperation after cholecysto-enterostomy].

Treated were 129 patients, who earlier underwent cholecysto-enterostomy in periampullary tumors. At the period of from 3.5 to 5 weeks after the first operation, these patients need thorough clinico-instrumental examination, they should be given aid at a specialized in-patient department.

Ampulla of Vater↗