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Biomedical subjects

A N Lotarev

Publications and source records attributed to A N Lotarev.

6 recordsLinked to original sources

[Effect of low-intensity impulse diffuse laser radiation on the functional state of the visual analyzer].

Studies were performed on rabbits to investigate single stimulation of the rabbit's eye with low-intensive dissipated laser radiation at 0.53 micron and their influence on the bioelectric activity of the retina which was evaluated at the amplitude b-ERG wave. Established was the dependence of the stimulus' disadapting effect on the laser radiation density within the range of 1 x 10(-11)-3.5 x 10(-4) J.cm-2. The radiation beams with at frequency of 50 Hz and density of 1 x 10-11 J.cm-2 or less did not exhibit any disadapting effect on the retina. Radiation density at 1 x 10(-9)-1 x 10(-7) J.cm-2 decreased the b-ERG wave amplitude only at the time of stimulating the retina. This biological effect can be regarded as an adequate physiological reaction to the stimuli. Radiation exposition at 1 x 10(-6)-4 x 10(-4) J x cm-2 caused a decrease in b-ERG wave after the retina had been stimulated.

Animals↗

[Microelectrode study of the cellular reactions of the taste bud in the frog Rana temporaria].

Microelectrophysiological studies reveal two types of cells in the taste bud of frog which differ by the level of their membrane potential. During vertical implantation of microelectrode through the apical part of the taste bud, the potential difference in the upper layer amounts to 15 mV. Further implantation of the electrode results in a stepwise decrease of the potential difference up to 27 mV. Cells of the deeper layer are located 12-24 micron lower from the apical surface. Stimulation of cells by solutions of chemical substances is accompanied by cell depolarization, its amplitude being proportional to stimulus concentration. The steepness of depolarization depends on the modality of the stimulus, being maximum for salts. The data obtained suggest that cells of the second layer, with a higher resting membrane potential level, are taste ones.

Animals↗

[Dynamics of membrane potential of limb muscular tissue in acute hypoxia induced by blood loss].

The authors studied the frequency dependence of the membrane potential of the rat quadriceps femoris muscle fibres in acute hypoxia caused by blood loss on its severity and duration. The membrane potential reduced with the gradual development of metabolic disorders in the tissue. Approximation revealed an exponential character of the dependence of the cell membrane potential on the severity and duration of hypoxia. The severity of the hypoxic disorders in the tissue can be judged from the value of the membrane potential.

Animals↗