PubMed Health⌕ Search

Biomedical subjects

A N Makarov

Publications and source records attributed to A N Makarov.

11 recordsLinked to original sources
PubMed2003

[Antihypertensive treatment with eprosartan mesilate of patients in acute and late periods of ischemic stroke].

Twenty patients with stroke of hemisphere localization developed as a result of arterial hypertension were treated with eprosartan mesilat. An estimation of the drug efficacy was conducted in comparison with other hypotensive medicines (control group). Eprosartan was used in dosage 600 mg daily. The study was carried out during 12 months, along with a monitoring of the most relevant hemodynamic indices, evaluation of somatic and neurological state of the patients as well as of some neuropsychological functions and quality of life, statistical significance of the results being determined. Pronounced hypotensive effect of the drug was found both in acute and late periods of stroke. Eprosartan mesilat monotherapy was effective in 75% of the patients. The most important feature proved to be a decrease of arterial pressure variability from the first days of the treatment, less frequency of secondary strokes being detected as well.

Acrylates↗
PubMed1996

[Mechanisms of resistance to quinolones and current level of sensitivity of clinically important microorganisms to ofloxacin].

The data on the mechanisms of microbial resistance to fluoroquinolones are presented. Comparison of the susceptibility levels of the microorganisms isolated on the territory of Russia showed that among the gram-negative opportunistic isolates 84 per cent was susceptible to ofloxacin, 45 per cent to ampicillin/sulbactam, 70 per cent to cefotaxime, 80 per cent to ceftazidime, 85 per cent to amikacin and 62 per cent to gentamicin. Among the Salmonella, Shigella and Vibrio cholerae isolates no strains were resistant to ofloxacin. Among the Salmonella isolates from patients more than 30 per cent was resistant to ampicillin, chloramphenicol, trimethoprim/sulmethoxasole and tetracycline. Among the Salmonella isolates 65 to 90 per cent was resistant to the antibiotics. Among the V.cholerae isolates 59 per cent was resistant to trimethoprim/sulmethoxasole.

Anti-Infective Agents↗
PubMed1996

[Characterization of antimicrobial properties of cefpirome].

The results of a multicentre investigation of antibiotic susceptibility in 800 clinical isolates were analyzed. The levels of susceptibility to cefpirome and other antibiotics in gram-negative organisms with inducable production of chromosomal beta-lactamases (Enterobacter, Serratia, Citrobacter and others) were compared and the advantages of cefpirome over other cephalosporins were shown: 89 per cent of the susceptible strains against 58 to 78 per cent. With respect to other microorganisms the advantages of cefpirome were less pronounced.

Cell Membrane Permeability↗
PubMedDate not supplied

[Status and prospects for development of medical equipment at the state-of-the-art "Axion Holding" "Izhevskiy Motor Plant"].

The joint stock company "Izhevsky Motor Plant "AXION-HOLDING" is a large manufacturer in different industrial branches, including medical equipment. The paper presents data on the status-of-the-art and prospects of development in producing medical equipment in several areas, including information on specific articles that are manufactured and promising.

Equipment and Supplies↗