PubMed HealthSearch

Biomedical subjects

A N Remizov

Publications and source records attributed to A N Remizov.

10 recordsLinked to original sources

[An experimental basis for cochlear prosthesis].

The experimental studies on cochlear prosthesis, performed at the II Moscow's medical Institute since 1981, are described. Electrophysiological and morphological results from the trial of an original electronic prosthesis, which transduces sound into electric oscillations, are presented. Data are given on morphological studies, referring to the influence of cochlear implants on the basal curve of the cochlea, to the internal structures of the cochlea and of the acoustic zone in the cortex of the large hemispheres. The results from the performed experiments show the efficiency of the described method for cochlear prosthesis and the possibility for its usage in the clinical practice.

Animals

[Study of the effect of corticosterone on erythrocyte membranes by the spin label method].

Influence of corticosterone on the hare's erythrocyte ghosts is studied by the spin-label method. There exists a correlation between the maximal variation region in the rotational diffusion "frequency" of the spin-labels, covalently linked with the membrane protein, and the hormones concentration range within which the effect of corticosterone on the functions of the erythrocyte membranes manifests itself to the greatest degree (permeability to ions, hemolytic effects, etc).

Animals

[The course on medical physics].

The definition of medical physics is given, the main directions of the course are described, and some practical examples are provided. Analysis is made of the status of the problem concerned with teaching medical physics.

Curriculum

[Free radicals formed during UV-irradiation of unsaturated fatty acids containing peroxidation products].

On the irradiation of oxidized linolic acid an assymetric ESR signal with g-factor 2.0039 and the linewidth 30--33 Oe has been registered. The signal could be the result of photolysis of hydroperoxides. During prolonged irradiation of all the samples accumulation of alkyl radicals characterized by a symmetric signal with a well-defined ultrafine structure has been observed. An increase of the sample temperature up to 87 K in the presence of oxygen was preceded by transformation of alkyl radical R into RO2. All the radicals disappeared at the temperature of 160 K. All these processes seem to be the first phases of photoperoxidation of unsaturated fat acids in lipid-containing systems, including biological membranes.

Electron Spin Resonance Spectroscopy

[Free radicals formed during UV-irradiation of biological membrane lipids].

Formation of free radicals under UV-irradiation of egg phosphatidyl choline, and synthetic phosphatidyl cholines and their analogs, as well as of their model compounds was studied. When saturated fat lipids are UV-irradiated radicals--CH2CH2 are accumulated at the expense of the breakage of--CH2CH2--COOH-bond. Radicals CH3--OCH2, HCO are formed in aminoalcohols due to the breakage of --OCH2--CH2N+(CH3)3- and--CH2--N+(CH3)3-bonds. It has been found that in natural and synthetic phospholipids radicals are formed in the course of photochemical reactions in complex ether and amine groups. The mechanism of radical formation is discussed.

Amino Alcohols