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Biomedical subjects

A N Studitskiĭ

Publications and source records attributed to A N Studitskiĭ.

At least 19 recordsLinked to original sources
PubMed1988

[Ultrastructure of neuromuscular synapses during administration of dexamethasone].

Dexamethasone administration to rats at a dose of 100 micrograms/100 g body weight for 10 days resulted in the appearance of large synaptic vesicles in axon terminals, migration of synaptic vesicles to synaptic slits, local broadening of synaptic slit, proliferation of mitochondria in pre- and postsynaptic zones of the axomuscular synapses, destruction of myofibrils and other organelles in the postsynaptic area and the presence of lysosomes in this region.

Animals↗
PubMed1986

[Effect of the survival of xenografts in animals].

A method of free xenotransplantation of skeletal muscles (from rat donors) to another species (mouse, hamster or guinea pig) has been elaborated. It has been shown that the muscle (gastrocnemius) of the donor animal acquires the property to survive and develop when wrapped in a cellophane film. The muscle should be kept wrapped in a cellophane film for up to 330 days. The transplanted muscle can survive and develop, acquiring normal histological structure, typical motor innervation and contractile activity. For xenotransplantation a fragment of the donor muscle corresponding to the size of the removed recipient muscle was excised. Mouse and hamster recipients were last examined 330 days, and guinea pigs 60 days after transplantation.

Animals↗
PubMed1985

[Ultrastructural changes in the red muscle fibers of the quadriceps muscle of the rat femur during increased motor activity].

Experiments on rats were made to study the effect of physical exercise running in a treadbahn on ultrastructure of skeletal muscle fibers. The biphasic mechanism of muscle contractile activity was shown. The processes of destruction occurring in red muscle fibers of the intensely working quadriceps femoris were manifested by enlargement of T system and sarcoplasmic reticulum elements, mitochondrial matrix swelling, cryst destruction, vacuolar degeneration of part of the mitochondria, and destruction of individual myofibrils. In addition to destructive changes, the muscle exhibited the recovery processes--physiological regeneration. Those processes included large accumulations of the mitochondria beneath the plasma membrane of muscle fibers, the presence of small mitochondria, division of the mitochondria, transformation of myosatellitocytes to myoblasts, the presence of centrioles in endotheliocytes, and so forth.

Animals↗
PubMed1976

[Severbal new problems in evolutionary histology].

The classical evolutionary histology as a most important section of theoretical morphology created by workd of A.A. Zavarzin, N.G. Khlopin and A.V. Rumiantsev needs a revision on the basis of achievements of modern morphology, first of all the experimental morphology which have accumulated a vast factual material on a repeated (regenerative, transplantational, inflammatory) morphogenesis, brought about on the basis of the constructive (plastic) activity of tissues which escaped the researchers' attention in the classical period of development of evolutionary histology. A demand to create a new system of the tissue, based on characteristics of their plastic (constructive) activity became urgent. The proposed attempt of the evolutionary classification of tissues comes from the experience of researches of the constructive (plastic) activity of tissues, with the Darwin--Severtsov rule of the dependence of every individual and phylogenetic change of the organization of its pre-existing state taken into consideration.

Animals↗